81102-97-8Relevant academic research and scientific papers
Phenothiazine-based chalcones as potential dual-target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO-A, MAO-B)
Yamali, Cem,Engin, Feyza Sena,Bilginer, Sinan,Tugrak, Mehtap,Ozmen Ozgun, Dilan,Ozli, Gulsen,Levent, Serkan,Saglik, Begum Nurpelin,Ozkay, Yusuf,Gul, Halise Inci
, p. 161 - 171 (2020/10/19)
Chalcones targeting neurodegenerative diseases have been known as attractive structures in drug design and discovery. In this study, phenothiazine-based chalcones as ChEs and MAOs inhibitors were designed and synthesized via base-catalyzed Claisen-Schmidt
Microwave assisted synthesis and SAR studies of novel hybrid phenothiazine analogs as potential antitubercular agents
Pemmadi, Raghuveer Varma,Kurre, Puma Nagasree,Guruvelli, Padma Vijaya Sangeetha,Jamullamudi, Risy Narnratha,Muthyala, Murali Krishna Kumar
, p. 556 - 566 (2019/05/21)
The present work has been initiated based on the interest driven by phenothiazine based neuroleptics with a special focus on thioridazine. Their clinically useful spectrum of anti-TB profile is the motivating factor. A hybrid pharmacophore has been design
