81159-59-3Relevant academic research and scientific papers
(2-Chloralkylidene)amine Oxide as Alkylation Reagents; Reactions with Amines and the Anions of Dialkyl Malonates
Lidor, Rami,Shatzmiller, Shimon
, p. 226 - 230 (2007/10/02)
Aminolysis of N-(2-chloroethylidene)cyclohexylamine oxide (1) in ether at 25 deg C with the amines 2a-d yields the (2-aminoalkylidene)amine oxides 3a-d.The aminolysis of 1 with the tertiary amines 5a-c yields the ammonium salts 6a-c, and the reaction of N-(2-chloropropylidene)cyclohexylamine oxide (8) in benzene at 60 deg C with the anions of dialkyl malonates (7a,b) yields the nitrones 9a,b.The hydrolytic cleavage of 9a,b to the aldehydes 10a,b is described.
