81177-24-4Relevant academic research and scientific papers
The synthesis of the 2, 3-difluorobutan-1, 4-diol diastereomers
Szpera, Robert,Kovalenko, Nadia,Natarajan, Kalaiselvi,Paillard, Nina,Linclau, Bruno
supporting information, p. 2883 - 2887 (2018/01/17)
The diastereoselective synthesis of fluorinated building blocks that contain chiral fluorine substituents is of interest. Here we describe optimisation efforts in the synthesis of anti-2, 3-difluorobutane-1, 4-diol, as well as the synthesis of the corresponding syn-diastereomer. Both targets were synthesised using an epoxide opening strategy.
Synthesis of 3,4-Ethylenedioxythiophene (EDOT) from (Z)-but-2-ene-1,4-diol or but-2-yne-1,4-diol
Hachiya, Iwao,Matsumoto, Tomohiro,Inagaki, Tatsuhiko,Takahashi, Atsushi,Shimizu, Makoto
experimental part, p. 449 - 460 (2011/04/24)
3,4-Ethylenedioxythiophene (EDOT) was synthesized from commercially available (Z)-but-2-ene-1,4-diol or but-2-yne-1,4-diol using epoxidation, etherification, and thiophene formation. The Japan Institute of Heterocyclic Chemistry.
A lipase-mediated synthesis of single enantiomeric trans-epoxides via convergence of racemic mixtures
Taniguchi, Takahiko,Ogasawara, Kunio
, p. 4383 - 4386 (2007/10/03)
A new lipase-mediated methodology has been devised for the preparation of single enantiomeric trans-epoxides from unsymmetrical cis-olefin precursors via enantiomeric convergence of racemic intermediates.
Enantiospecific synthesis of [(2'S, 3'S)-bis(hydroxymethyl)azetidin-1-yl]pyrimidine nucleosides as potential antiviral agents
Hosono,Nishiyama,Yamamura,Izawa,Kato,Terada
, p. 13335 - 13346 (2007/10/02)
The enantiospecific synthesis of [(2'S, 3'S)-bis(hydroxymethyl)azatidin-1-yl]pyrimidine nucleotides 22, 25, and 27 was achieved via construction of the base on the 1-aminoacetidine 18 prepared from (+)-diethyl-L-tartrate, and they are the first members of
