81214-69-9Relevant academic research and scientific papers
Design and synthesis of novel phthalocyanines as potential antioxidant and antitumor agents starting with new synthesized phthalonitrile derivatives
Abdel-Latif, Ehab,El-Badrawy, Afnan M.,Fadda, Ahmed A.,Selim, Yasser A.
, p. 34300 - 34308 (2021/12/08)
New phthalonitrile derivatives formed from reactions of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) were considered as the key intermediates for the synthesis of new phthalocyanines. Moreover, new phthalonitrile derivatives 2, 5, 9, 10, 15 and 16 reac
PYRIDAZINES CONDENSED WITH A HETERO RING, I. STRUCTURE OF PYRIDOAMINOPYRIDAZINES, I. SEPARATION AND STRUCTURE PROOF OF THE ISOMERIC MONOCHLORO COMPOUNDS PREPARED BY HYDROLYSIS OF 5,8-DICHLOROPYRIDOPYRIDAZINE
Kormendy, K.,Kovacs, T.,Szulagyi, J.,Ruff, F.,Kovesdi, I.
, p. 167 - 182 (2007/10/02)
A new method has been developed for the separation and purification of the isomeric monochloro compounds (2, 3) resulting from the hydrolysis of 5,8-dichloropyridopyridazine (1).The mobility of the chlorine atoms in compound 1 depends on the conditions of the hydrolysis.In alkaline solutions compounds 2 and 3 are formed in nearly identical amounts, whereas in acid hydrolysis the ratio of isomers is shifted towards the formation of 3.The structural position of the chlorine atom in the isomers has been verified by synthesis; the results (2: 8-Cl, and 3: 5-Cl) are in accordance with the literature data.The formation of compounds such as 24, 25 in the aminolysis of 2 and 3 substantiates the structures of the aminopyridopyridazinones made from the quinoline acid imide derivatives (e.g., 21 ---> 24, 25).
