81244-03-3

Upstream product

• 118-00-3 G 
• 81243-96-1 9-((2R,3R,3aS,9aR)-3-Hydroxy-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-1,9-dihydro-purin-6-one 
• 69304-44-5 3',5'-O-1,1,3,3-tetraisopropyldisiloxan-1,3-diyl-guanosine 
• 110-87-2 3,4-dihydro-2H-pyran 
• 81244-00-0 2-{[(4-Methoxy-phenyl)-diphenyl-methyl]-amino}-9-[(2R,3R,3aR,9aR)-5,5,7,7-tetraisopropyl-3-(tetrahydro-pyran-2-yloxy)-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl]-1,9-dihydro-purin-6-one 

Downstream Products

• 81244-10-2 Dithiophosphoric acid O-[(2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester 
• 81244-06-6 9-[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-3-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-yl]-2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-1,9-dihydro-purin-6-one 

Relevant academic research and scientific papers

SYNTHESIS OF OLIGORIBONUCLEOTIDES BY USE OF S,S-DIPHENYL N-MONOMETHOXYTRITYL RIBONUCLEOSIDE 3'-PHOSPHORODITHIOATES

The fully protected ribonucleotide units (6a-d) have been synthesized in 42-62 percent overall yields by the 5- or 6-step reactions.The dimethoxtrityl, monomethoxytrityl, tetrahydropyran-2-yl, and phenylthio groups were introduced onto the 5'-OH, exo-amin

NEW TYPE OF PREFABRICATED FULLY PROTECTED RIBONUCLEOTIDE MONOMER UNITS AS USEFUL SYNTHETIC INTERMEDIATES IN RAPID OLIGORIBONUCLEOTIDE SYNTHESIS

Oligoribonucleotide synthesis has been done by employing newly constructed fully protected ribonucleotide units, S,S-diphenyl 5'-O-dimethoxytrityl-2'-O-tetrahydropyranyl-N-monomethoxytrityl-nucleoside 3'-phosphorodithioates 7.The units were found to be us