81262-71-7Relevant articles and documents
Design, synthesis, and pharmacological characterization of some 2-substituted-3-phenyl-quinazolin-4(3H)-one derivatives as phosphodiesterase inhibitors
Amin, Kamilia M.,Hegazy, Gehan H.,George, Riham F.,Ibrahim, Nahla R.,Mohamed, Nada M.
, (2021/05/13)
Some 3-phenyl-quinazolin-4(3H)-one-2-thioethers (3a–e, 5a,b, 7a–e, 9a–d, 10a–d, and 12) along with 2-aminoquinazoline derivatives 13a–c were prepared and screened for their in vitro phosphodiesterase (PDE) inhibitory activity. Some compounds such as 7d,e,
Monoamine oxidase inhibitory and CNS activities of some quinazolinones
Lata,Satsangi,Srivastava,Kishor
, p. 24 - 27 (2007/10/02)
16 new compounds have been synthesised in the series of 3-aryl-2-(1'-aryl-piperazin-4'-yl-carboxamidomethyl)-mercapto-quinazolinones . The compounds showed interesting results in anticonvulsant, hypnotic and monoamine oxidase (MAO) inhibitory screenings a