812654-63-0Relevant academic research and scientific papers
A mild and efficient protocol for the protection of 3-hydroxychromones under phase-transfer catalysis
Dziuba, Dmytro,Benhida, Rachid,Burger, Alain
, p. 2159 - 2164 (2011)
A mild and efficient protocol for the introduction of different protecting groups on 3-hydroxychromones (3-HCs) under phase-transfer catalysis conditions in toluene or dichloromethane/aqueous potassium hydroxide system in the presence of crown ether has been developed. The method is useful for the protection of base-sensitive chromone derivatives. Protected chromones are easier to handle and to purify, and therefore suitable for further chemical transformations. The protecting groups were cleaved cleanly using standard conditions. Georg Thieme Verlag Stuttgart ? New York.
