81275-41-4

Basic information

• Product Name: methyl 5-O-benzyl-2,3-O-isopropylidene-α-D-ribofuranoside
• CAS NO: 81275-41-4
• Molecular Weight: 294.348
• Mol File: 81275-41-4.mol

Chemical Properties

• CAS DataBase Reference: methyl 5-O-benzyl-2,3-O-isopropylidene-α-D-ribofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-O-benzyl-2,3-O-isopropylidene-α-D-ribofuranoside(81275-41-4)
• EPA Substance Registry System: methyl 5-O-benzyl-2,3-O-isopropylidene-α-D-ribofuranoside(81275-41-4)

Safety Data

• Hazardous Substances Data: 81275-41-4(Hazardous Substances Data)

Upstream product

• 532-20-7 D-Ribose 
• 1824-96-0 methyl ribofuranoside 
• 58763-00-1 ((3aR,4R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 
• 100-39-0 benzyl bromide 

Downstream Products

• 69603-05-0 methyl-(O⁵-benzyl-O²,O³-carbonyl-β-D-ribofuranoside) 
• 67737-49-9 methyl 5-O-benzyl-α-D-ribofuranoside 
• 67737-48-8 methyl 5-benzyloxy-β-D-ribofuranoside 

Relevant articles and documents

Synthesis of methyl 2-O-allyl-(and 3-O-allyl-)5-O-benzyl-β-D-ribofuranoside

D-Ribose was converted into methyl 5-O-benzyl-β-D-ribofuranoside and this, on tin-mediated allylation, gave a mixture of the 2-O-allyl and 3-O-allyl derivatives which were separated by chromatography. The more polar isomer was characterised as the 3-O-allyl derivative after conversion via 3-O-allyl-5-O-benzyl-1,2-O-isopropylidene-α-D-ribofuranose (which was also synthesised from 3-O-allyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose) into the known 5-O-benzyl-1,2-O-isopropylidene-α-D-ribofuranose. Methyl 3-O-allyl-5-O-benzyl-β-D-ribofuranoside was converted into methyl 2-O-allyl-5-O-benzyl-β-D-ribofuranoside via methyl 2-O-allyl-5-O-benzyl-3-O(prop-1-enyl)-β-D-ribofuranoside.