81278-80-0

Basic information

• Product Name: 2-aminophenyl 4-(tert-butyl)benzenesulfonate
• Synonyms: 2-aminophenyl 4-(tert-butyl)benzenesulfonate
• CAS NO: 81278-80-0
• Molecular Weight: 305.398
• Mol File: 81278-80-0.mol

Chemical Properties

• CAS DataBase Reference: 2-aminophenyl 4-(tert-butyl)benzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aminophenyl 4-(tert-butyl)benzenesulfonate(81278-80-0)
• EPA Substance Registry System: 2-aminophenyl 4-(tert-butyl)benzenesulfonate(81278-80-0)

Safety Data

• Hazardous Substances Data: 81278-80-0(Hazardous Substances Data)

Upstream product

• 15084-51-2 4-tert-butylbenzenesulfonyl chloride 
• 95-55-6 2-amino-phenol 

Downstream Products

• 81256-09-9 4-(tert-butyl)-N-(2-hydroxyphenyl)benzenesulfonamide 

Relevant articles and documents

Phenylbenzenesulfonates and -sulfonamides as 17β-hydroxysteroid dehydrogenase type 2 inhibitors: Synthesis and SAR-analysis

17β-Hydroxysteroid dehydrogenase type 2 (17β-HSD2) converts the potent estrogen estradiol into the weakly active keto form estrone. Because of its expression in bone, inhibition of 17β-HSD2 provides an attractive strategy for the treatment of osteoporosis

Substitution at Tetracoordinate Sulfur(VI). Rearrangement of 2-Aminoaryl Arenesulfonates to N-(2-Hydroxyaryl)arenesulfonamides

A series of eight 2-aminoaryl arenesulfonates upon treatment by strong bases rearranged intramolecularly to their corresponding N-(2-hydroxyaryl)arenesulfonamides as did the related tosylates derived from 2-amino-3-hydroxypyridine, 1-amino-2-naphthol, and