81282-89-5

Upstream product

• 81282-94-2 5-[(E)-2-(2,6-Dichloro-phenyl)-vinyl]-3-methyl-4-nitro-isoxazole 
• 123-54-6 acetylacetone 
• 1123-49-5 3,5-dimethyl-4-nitroisoxazole 
• 83-38-5 2,6-dichlorobenzaldehyde 

Downstream Products

• 1242340-78-8 C₂₇H₂₀Cl₂N₆O₇ 
• 98735-01-4 5-[2-(2,6-Dichloro-phenyl)-2-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-ethyl]-3-methyl-4-nitro-isoxazole 
• 98239-43-1 5-[2-(2,6-Dichloro-phenyl)-2-(3,5-dimethyl-1H-pyrazol-4-yl)-ethyl]-3-methyl-4-nitro-isoxazole 
• 78636-43-8 C₁₇H₁₅Cl₂N₃O₄ 

Relevant academic research and scientific papers

Multi-component synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N- oxides

A three component one-pot protocol was investigated for the synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N-oxides from commercially available materials.

Chemistry of Heterocylces: Part VIII - Synthesis of Isoxazolylethylpyrazoles

The base-catalysed addition of acetylacetone to 3-methyl-4-nitro-5-styrylisoxazoles (II) leads to the Michael adducts 3-pentane-2,4-diones (III).These β-diketones (III) undergo cyclization with hydrazine sulphate and phenylhydrazine to furnish pyrazoles (IV) and N-phenylpyrazoles (V), respectively.

Ethylene-diheterocycles: Part I - Synthesis of 5--3-methyl-4-nitroisoxazoles

Michael addition of acetylacetone to 3-methyl-4-nitro-5-styrylisoxazoles (I) in triethylamine leads to 3--2,4-pentanediones (II).The pentanediones (II) undergo cyclisation with hydroxylamine to give 5-ω