81310-40-9

Upstream product

• 70477-21-3 2-chloro-3-methylbutanenitrile 
• 98-95-3 nitrobenzene 
• 89278-07-9 3-methyl-2-(phenylthio)butanenitrile 
• 5558-29-2 3-methyl-2-phenyl-butyronitrile 
• 75-30-9 2-iodo-propane 
• 109-69-3 n-Butyl chloride 
• 865-33-8 potassium methanolate 
• 555-21-5 4-Nitrophenylacetonitrile 
• 121-73-3 3-Nitrochlorobenzene 
• 100-00-5 4-chlorobenzonitrile 

Downstream Products

• 80607-80-3 3-Methyl-2-(4-nitrophenyl)buttersaeure 

Relevant academic research and scientific papers

Vicarious Nucleophilic Substitution of Hydrogen in Nitroarenes with α-Substituted Nitriles and Esters. Direct α-Cyanoalkylation and α-Carbalkoxyalkylation of Nitroarenes

Carbanions generated from alkanenitriles bearing α-chloro, α-OR, or α-SR groups and from aliphatic esters bearing α-SR groups react with mononitroarenes to replace hydrogen atoms of the nitroaromatic ring ortho or para to the nitro group with α-cyanoalkyl or α-carbalkoxyalkyl substituents.The nucleophilic replacement of hydrogen with such carbanions proceeds faster than substitution of halogen ortho or para to the nitro group.

Substituted butanoic acid esters

The substituted butanoic acid esters 2-(4-azidophenyl)-3-methylbutanoic acid, α-cyano-3-phenoxybenzyl ester and 2-(4-azidophenyl)-3-methylbutanoic acid, 3-phenoxybenzyl ester are useful as insecticides.