81310-68-1

Usage

Uses

Used in Organic Synthesis:
2-(3-bromophenyl)-propanol is utilized as a reagent in organic synthesis for its ability to participate in various chemical reactions, facilitating the formation of a wide range of organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(3-bromophenyl)-propanol is employed as a building block for the preparation of pharmaceutical compounds, leveraging its structural features to enhance the properties of potential drugs.
Used in Drug Development:
2-(3-bromophenyl)-propanol holds promise in drug development, where it may contribute to the discovery and design of new therapeutic agents, particularly through its integration into the molecular structures of candidate compounds.
Used as an Intermediate in Chemical Production:
Furthermore, 2-(3-bromophenyl)-propanol serves as an intermediate in the production of other organic compounds, highlighting its versatility and importance in the broader scope of chemical synthesis across different industries.

Upstream product

• 67-56-1 methanol 
• 28229-69-8 2-(3-bromophenyl)ethan-1-ol 
• 59452-90-3 2-(3-bromophenyl)propanal 
• 25108-58-1 1-bromo-3-isopropenylbenzene 
• 30951-66-7 2-(3-bromophenyl)-2-propanol 

Relevant academic research and scientific papers

Highly efficient NHC-iridium-catalyzed β-methylation of alcohols with methanol at low catalyst loadings

The methylation of alcohols is of great importance since a broad number of bioactive and pharmaceutical alcohols contain methyl groups. Here, a highly efficient β-methylation of primary and secondary alcohols with methanol has been achieved by using bis-N-heterocyclic carbene iridium (bis-NHC-Ir) complexes. Broad substrate scope and up to quantitative yields were achieved at low catalyst loadings with only hydrogen and water as by-products. The protocol was readily extended to the β-alkylation of alcohols with several primary alcohols. Control experiments, along with DFT calculations and crystallographic studies, revealed that the ligand effect is critical to their excellent catalytic performance, shedding light on more challenging Guerbet reactions with simple alcohols. [Figure not available: see fulltext.].

Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof

1-[(3- or 4-Benzoylphenyl)-lower-alkyl]-[(CH2)n --N=B]-substituted-piperidines, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents, are prepared by alkylation of an appropriate subs

Benzoylphenyl lower alkanoyl piperidines

1-[(3- or 4-Benzoylphenyl)-lower-alkyl]-[(CH2)n -N=B]-substituted-piperidines, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents, are prepared by alkylation of an appropriate subst

4-[[3-[α-Aminobenzyl]phenyl]methyl]morpholine and 4-[-[3-benzoylphenyl]ethyl]morpholine

N-{2, 3- and 4-[R1 -(phenyl)-C(=X)]-phenyl-lower-alkyl}amines, useful as anti-inflammatory agents, are prepared either by reduction of 2-, 3- or 4-[R1 -(phenyl)-CO]-phenyl-lower-alkanoylamines, which are also useful as anti-inflammatory agents; by benzoylating a phenyl-lower-alkylamine; by reaction of a 2-, 3- or 4-lithiophenyl-lower-alkylamine with a R1 -(phenyl)-carboxaldehyde, a R1 -(phenyl)-lower-alkyl ketone or a R1 -(phenyl)-carbonitrile; by reaction of a 2-, 3- or 4-[R1 -(phenyl)-CO]-phenyl-lower-alkyl tosylate with an appropriate amine; or by transformations involving manipulations of a carbonyl or carbinol group.