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1,2,3,5-tetrahydro-Spiro[4H-1-benzazepine-4,1''-[2]cyclopentene]-3''-carboxylic acid, commonly referred to as SPIRO, is a distinctive chemical compound characterized by its spiro skeleton and a carboxylic acid functional group. With a molecular formula of C20H22N2O2 and a molar mass of 322.40 g/mol, SPIRO exhibits intriguing biological activities and has garnered attention for its potential therapeutic applications. Its unique molecular structure positions it as a promising candidate for further research and development in various fields.

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  • 1,2,3,5-Tetrahydro-spiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid

    Cas No: 813426-13-0

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  • 813426-13-0 Structure
  • Basic information

    1. Product Name: 1,2,3,5-tetrahydro-Spiro[4H-1-benzazepine-4,1''-[2]cyclopentene]-3''-carboxylic acid
    2. Synonyms: 1,2,3,5-tetrahydro-Spiro[4H-1-benzazepine-4,1''-[2]cyclopentene]-3''-carboxylic acid;Spiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid, 1,2,3,5-tetrahydro-
    3. CAS NO:813426-13-0
    4. Molecular Formula: C15H17NO2
    5. Molecular Weight: 243.30098
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 813426-13-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 451.81 °C at 760 mmHg
    3. Flash Point: 227.047 °C
    4. Appearance: /
    5. Density: 1.24
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 1,2,3,5-tetrahydro-Spiro[4H-1-benzazepine-4,1''-[2]cyclopentene]-3''-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1,2,3,5-tetrahydro-Spiro[4H-1-benzazepine-4,1''-[2]cyclopentene]-3''-carboxylic acid(813426-13-0)
    11. EPA Substance Registry System: 1,2,3,5-tetrahydro-Spiro[4H-1-benzazepine-4,1''-[2]cyclopentene]-3''-carboxylic acid(813426-13-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 813426-13-0(Hazardous Substances Data)

813426-13-0 Usage

Uses

Used in Pharmaceutical Industry:
SPIRO is utilized as a pharmaceutical agent for its potential therapeutic applications. Its unique spiro structure and carboxylic acid group contribute to its biological activities, making it a candidate for the development of new drugs targeting various diseases and conditions.
Used in Chemical Research:
In the field of chemical research, SPIRO serves as a subject of study for understanding its properties, reactivity, and potential applications. Its unique structure allows researchers to explore new synthetic pathways and investigate its interactions with other molecules, paving the way for the discovery of novel compounds and materials.
Used in Drug Design and Development:
SPIRO is employed in drug design and development due to its potential as a lead compound. Its spiro skeleton and carboxylic acid group can be modified to create new derivatives with improved pharmacological properties, such as enhanced potency, selectivity, and bioavailability. This makes SPIRO a valuable starting point for the development of innovative therapeutic agents.
Used in Material Science:
In material science, SPIRO can be explored for its potential use in the creation of new materials with unique properties. Its spiro structure and functional groups may contribute to the development of advanced materials with applications in various industries, such as electronics, coatings, and adhesives.

Check Digit Verification of cas no

The CAS Registry Mumber 813426-13-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,1,3,4,2 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 813426-13:
(8*8)+(7*1)+(6*3)+(5*4)+(4*2)+(3*6)+(2*1)+(1*3)=140
140 % 10 = 0
So 813426-13-0 is a valid CAS Registry Number.

813426-13-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name spiro[1,2,3,5-tetrahydro-1-benzazepine-4,3'-cyclopentene]-1'-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:813426-13-0 SDS

813426-13-0Downstream Products

813426-13-0Relevant articles and documents

Novel solid forms of (4R)-1-[2-chloro-5-fluorobenzoyl)amino-3-methoxybenzoyl]-1,2,3,5- tetrahydro-spiro[4h-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid

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Page/Page column 11, (2008/06/13)

The present invention relates to novel solid forms of (4R)-1-[4-(2-chloro-5-fluorobenzoyl)amino-3-methoxybenzoyl]-1,2,3,5-tetrahydro-spiro[4H-1-benzazepine-4,1′-[2]cyclopentene]-3′-carboxylic acid (formula (I)) useful for treating and/or preventing condit

Process for the preparation of nonpeptide substituted spirobenzoazepine derivatives

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Page 18, (2008/06/13)

Novel spirobenzoazepine compounds, novel processes for the preparation of nonpeptide substituted spirobenzoazepine derivatives, and novel processes for the preparation of intermediates in the preparation of such derivatives. Novel intermediates in the preparation of nonpeptide substituted spirobenzoazepine derivatives.

Substituted spirobenzazepines

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Page 16, (2008/06/13)

The invention is directed to nonpeptide substituted benzazepines of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension, among others disclosed. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.

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