813447-29-9Relevant articles and documents
N-[(3S)-Pyrrolidin-3-yl]benzamides as novel dual serotonin and noradrenaline reuptake inhibitors: Impact of small structural modifications on P-gp recognition and CNS penetration
Wakenhut, Florian,Allan, Gill A.,Fish, Paul V.,Jonathan Fray,Harrison, Anthony C.,McCoy, Rachel,Phillips, Stephen C.,Stobie, Alan,Westbrook, Dominique,Westbrook, Simon L.,Whitlock, Gavin A.
scheme or table, p. 5078 - 5081 (2010/03/24)
The structure-activity relationship and the synthesis of novel N-[(3S)-pyrrolidin-3-yl]benzamides as dual serotonin and noradrenaline monoamine reuptake inhibitors (SNRI) is described. Preferred compound 9 aka PF-184,298 is a potent SNRI with good selecti
