81358-65-8

Basic information

• Product Name: 3-BROMO-4-FLUOROBENZALDEHYDE DIMETHYL ACETAL
• Synonyms: 3-BROMO-4-FLUOROBENZALDEHYDE DIMETHYL ACETAL
• CAS NO: 81358-65-8
• Molecular Formula: C₉H₁₀BrFO₂
• Molecular Weight: 249.08
• Product Categories: Adehydes, Acetals & Ketones;Bromine Compounds;Fluorine Compounds
• Mol File: 81358-65-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-BROMO-4-FLUOROBENZALDEHYDE DIMETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-FLUOROBENZALDEHYDE DIMETHYL ACETAL(81358-65-8)
• EPA Substance Registry System: 3-BROMO-4-FLUOROBENZALDEHYDE DIMETHYL ACETAL(81358-65-8)

Safety Data

• Hazardous Substances Data: 81358-65-8(Hazardous Substances Data)

Upstream product

• 77771-02-9 3-bromo-4-fluorobenzaldehyde 
• 149-73-5 trimethyl orthoformate 
• 50981-12-9 sulfuric acid monohydrate 
• 67-56-1 methanol 

Downstream Products

• 81358-66-9 3-phenoxy-4-fluoro-benzaldehyde dimethyl acetal 
• 334019-14-6 2-fluoro-5-(dimethoxymethyl)benzaldehyde 
• 473415-90-6 [5-(dimethoxymethyl)-2-fluorophenyl](3-fluorophenyl)methanol 

Relevant articles and documents

Nickel-Catalyzed Chemoselective Acetalization of Aldehydes With Alcohols under Neutral Conditions

A molecularly defined NiII-complex catalyzing the chemoselective acetalization of aldehydes with alcohols under neutral conditions is reported. The reaction is general, efficient and showed a wide substrate scope (including aliphatic aldehydes) as well as excellent functional group tolerance. Reusability of the present nickel catalyst is also demonstrated.

NOVEL 1H-INDAZOLE COMPOUND

The present invention provides a novel 1H-indazole compound having an excellent JNK inhibitory action. More specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. Wherein R1 is a C6-C14 aromatic cyclic hydrocarbon group etc.; R2, R4 and R5 each independently represent a hydrogen atom, a halogen atom, a cyano group etc.; L is a single bond, or a C1-C6 alkylene group etc.; X is a single bond, or a group represented by -CO-NH- or -NH-CO-, etc.; and Y is a C3-C8 cycloalkyl group, a C6-C14 aromatic cyclic hydrocarbon group or a 5- to 14-membered aromatic heterocyclic group etc.

Preparation of 3-bromo-4-fluoro-benzaldehyde acetals and intermediates therefor

A process for the preparation of a 3-bromo-4-fluoro-benzaldehyde acetal of the formula: STR1 in which R each independently is a C1 to C4 alkyl group or the radicals R together are a C2 to C5 alkanediyl radical,