81369-81-5

Upstream product

• 80233-02-9 (S)-3-((E)-But-2-enyl)-3-(3,4-dimethoxy-phenyl)-dihydro-furan-2-one 
• 81309-82-2 (3R,5R)-5-Benzyloxymethyl-3-((E)-but-2-enyl)-3-(3,4-dimethoxy-phenyl)-dihydro-furan-2-one 
• 80233-01-8 (3S,5S)-3-((E)-But-2-enyl)-3-(3,4-dimethoxy-phenyl)-5-hydroxy-dihydro-furan-2-one 
• 81309-78-6 (R)-5-Benzyloxy-2-(3,4-dimethoxy-phenyl)-4-hydroxy-pentanenitrile 
• 81309-83-3 (3S,5R)-3-((E)-But-2-enyl)-3-(3,4-dimethoxy-phenyl)-5-hydroxymethyl-dihydro-furan-2-one 
• 81309-80-0 (R)-5-Benzyloxymethyl-3-(3,4-dimethoxy-phenyl)-dihydro-furan-2-one 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 
• 158531-92-1 (R)-(+)-2-(3,4-Dimethoxyphenyl)-2-((phenylsulfonyl)methyl)cyclobutanone ethylene acetal 
• 158531-97-6 (2S)-(-)-2-(3-Buten-1-yl)-2-(3,4-dimethoxyphenyl)cyclobutanone 
• 158531-98-7 (3S)-(-)-3-(3-Buten-1-yl)-3-(3,4-dimethoxyphenyl)tetrahydro-2-furanone 

Downstream Products

• 35714-44-4 Δ7-mesembrenone 
• 468-53-1 (-)-mesembrine 
• 81369-83-7 (S)-4-(3,4-Dimethoxy-phenyl)-4-(2-hydroxy-ethyl)-3-methylamino-cyclohex-2-enone 
• 80233-04-1 (S)-3a-(3,4-Dimethoxy-phenyl)-3,3a,4,5-tetrahydro-2H-benzofuran-6-one 
• 81369-82-6 (S)-3a-(3,4-Dimethoxy-phenyl)-3,3a,4,5-tetrahydro-2H-benzofuran-6-one 

Relevant academic research and scientific papers

A Highly Enantiocontrolled Strategy for the Synthesis of Benzylic Quaternary Carbon Centers. A Formal Total Synthesis of (-)-Mesebrine

A remarkable substituent effect by a trimethylsilyl group was observed on the enantioselectivity of the tandem asymmetric epoxidation and enantiospecific ring expansion of 2-cyclopropylidene-2-(4,5-dimethoxy-2-(trimethylsilyl)phenyl)ethanol (24), affordin

An Asymmetric Synthesis of Benzylic Quaternary Carbon Centers. A Formal Total Synthesis of (-)-Mesembrine

The optically pure sulfone 15, prepared by tandem asymmetric epoxidation and 1,2-rearrangement of the cyclopropylideneethanol 11 as a key step, was converted into the olefinic cyclobutanone 20 which was then transformed into the ketonic lactone 22 via the

ENANTIOSELECTIVE SYNTHESIS OF NATURAL MESEMBRINE USING (D)-MANNITOL AS A CHIRAL TEMPLATE, A MODEL STUDY FOR THE ENANTIOSELECTIVE SYNTHESIS OF THE AMARYLLIDACEAE ALKALOIDS

Enantioselective synthesis of (-)-mesembrine (1) has been achieved using (D)-mannitol with the intention of developing the enantioselective synthesis of the Amaryllidaceae alkaloids.