81376-88-7 Usage
Uses
Used in Pharmaceutical Industry:
Ethanone, 1-(3-ethoxy-2-pyridinyl)(9CI) is used as a key intermediate compound for the synthesis of various drugs and active ingredients. Its unique structure and properties make it a valuable component in the development of new pharmaceuticals.
Used in Antifungal Applications:
Ethanone, 1-(3-ethoxy-2-pyridinyl)(9CI) is used as an antifungal agent, exhibiting potential in inhibiting the growth and proliferation of various fungi, which can be beneficial in the treatment and prevention of fungal infections.
Used in Antimicrobial Applications:
Ethanone, 1-(3-ethoxy-2-pyridinyl)(9CI) is used as an antimicrobial agent, showing effectiveness against a range of bacteria. This property can be harnessed in the development of new antibiotics and antimicrobial treatments.
Used in Antiparasitic Applications:
Ethanone, 1-(3-ethoxy-2-pyridinyl)(9CI) is used as an antiparasitic agent, demonstrating potential in combating various parasites. This can be useful in the treatment and control of parasitic infections and diseases.
Used in Research and Development:
Ethanone, 1-(3-ethoxy-2-pyridinyl)(9CI) is used as a research compound for studying its biological activities and therapeutic potential. Its unique properties and potential applications make it an important compound in the field of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 81376-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,3,7 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 81376-88:
(7*8)+(6*1)+(5*3)+(4*7)+(3*6)+(2*8)+(1*8)=147
147 % 10 = 7
So 81376-88-7 is a valid CAS Registry Number.
81376-88-7Relevant academic research and scientific papers
Furopyridines.III.A New Synthesis of Furopyridine
Shiotani, Shunsaku,Morita, Hiroyuki
, p. 665 - 668 (2007/10/02)
A convenient synthesis of furopyridine and its 2- and 3-methyl derivatives from ethyl 3-hydroxypicolinate (1) is described.The hydroxy ester 1 was O-alkylated with ethyl bromoacetate or ethyl 2-bromopropionate to give the diester 2a or 2b.Cyclization of compound 2a afforded ethyl 3-hydroxyfuropyridine-2-carboxylate (3) which in turn was hydrolyzed and decarboxylated to give furopyridin-3-(2H)-one (4a).Cyclization of 2b gave the 2-methyl derivative 4b.Reduction of 4a and 4b with sodium borohydride yielded the corresponding hydroxy derivative 5a and 5b respectively, which were dehydrated with phosphoric acid to give furopyridine (6a) and its 2-methyl derivative (6b). 2-Acetylpyridin-3-ol (8) was converted to the ethoxycarbonylmethyl ether (9) by O-alkylation with ethyl bromoacetate, which was cyclized to give 3-methylfuropyridine-2-carboxylic acid (10).Decarboxylation of 10 afforded 3-methylfuropyridine (11).
