81381-93-3

Basic information

• Product Name: 3-quinuclidinyl-4-iodobenzilate
• Synonyms: 3-quinuclidinyl-4-iodobenzilate
• CAS NO: 81381-93-3
• Molecular Formula: C₂₁H₂₂INO₃
• Molecular Weight: 0
• Mol File: 81381-93-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 549°C at 760 mmHg
• Flash Point: 285.8°C
• Appearance: /
• Density: 1.61g/cm³
• Vapor Pressure: 6.9E-13mmHg at 25°C
• Refractive Index: 1.684
• CAS DataBase Reference: 3-quinuclidinyl-4-iodobenzilate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-quinuclidinyl-4-iodobenzilate(81381-93-3)
• EPA Substance Registry System: 3-quinuclidinyl-4-iodobenzilate(81381-93-3)

Safety Data

• Hazardous Substances Data: 81381-93-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C21H22INO3/c22-18-8-6-17(7-9-18)21(25,16-4-2-1-3-5-16)20(24)26-19-14-23-12-10-15(19)11-13-23/h1-9,15,19,25H,10-14H2

Upstream product

• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 81039-90-9 (RS)-1-azabicyclo<2.2.2>oct-3-yl (RS)-α-hydroxy-α-(4-aminophenyl)-α-phenylacetate 
• 81381-90-0 α-hydroxy-α-(4-aminophenyl)-α-phenylacetic acid 
• 88000-52-6 4-[(1-Aza-bicyclo[2.2.2]oct-3-yloxycarbonyl)-hydroxy-phenyl-methyl]-benzenediazonium; chloride 
• 81039-87-4 ethyl α-hydroxy-α-(4-nitrophenyl)-α-phenylacetate 
• 88000-53-7 α-hydroxy-4-nitro-α-phenylbenzeneacetonitrile 
• 81039-78-3 ethyl α-hydroxy-α-(4-aminophenyl)-α-phenylacetate 
• 88000-54-8 (R,S)-α-hydroxy-α-(4-nitrophenyl)-α-phenylacetic acid 
• 31029-96-6 1-(4-aminophenyl)-2-phenylethane-1,2-dione 
• 1144-74-7 4-nitrobenzophenone 
• 6581-06-2 quinuclidinyl benzilate 
• 81381-92-2 (RS)-1-azabicyclo<2.2.2>oct-3-yl (RS)-α-hydroxy-α-<4-<2-(3-methylpiperidin-1-yl)-1,2-diazaethylen-1-yl>phenyl>-α-phenylacetate 

Relevant articles and documents

A direct iodination method with iodine and silver triflate for the synthesis of SPECT and PET imaging agent precursors

A direct iodination method with iodine and silver triflate for the synthesis of SPECT and PET imaging agent precursors has been developed.

Analogues of 3-Quinuclidinyl Benzilate

A number of analogues of 3-quinuclidinyl benzilate (QNB) have been synthesized and their affinities to muscarinic receptor from rat or dog ventricular muscle measured.We have determined that the muscarinic receptor can to a different degree accomodate either a halogen in the ortho, meta, or para position of one phenyl ring or the repalcement of one phenyl ring with an alkyl group.Our in vitro competition studies show that the affinities lie within a 270-fold range, from the highest affinity compound, 3-quinuclidinyl α-hydroxy-α-cyclopentylphenylacetate (2), to the lowest affinity compound, 3-quinuclidinyl α-hydroxy-α-2-propargylphenylacetate (11).