81387-89-5 Usage
General Description
3,5-Dibromoindole is a chemical compound with the molecular formula C8H5Br2N. It is a member of the indole family of organic compounds, which are known for their distinct odor and are found in various natural products. 3,5-Dibromoindole is a pale yellow to dark brown solid that is insoluble in water but soluble in organic solvents. It is primarily used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and organic materials. The compound is also known for its potential biological activities and is being studied for its pharmacological properties, including its potential as an anti-bacterial and anti-cancer agent.
Check Digit Verification of cas no
The CAS Registry Mumber 81387-89-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,3,8 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 81387-89:
(7*8)+(6*1)+(5*3)+(4*8)+(3*7)+(2*8)+(1*9)=155
155 % 10 = 5
So 81387-89-5 is a valid CAS Registry Number.
81387-89-5Relevant articles and documents
Synthesis of bromoindole alkaloids from Laurencia brongniartii
Suarez-Castillo, Oscar R.,Beiza-Granados, Lidia,Melendez-Rodriguez, Myriam,Alvarez-Hernandez, Alejandro,Morales-Rios, Martha S.,Joseph-Nathan, Pedro
, p. 1596 - 1600 (2008/09/18)
A regioselective synthesis of N-carbomethoxy-2,3,5-tribromoindole (6) via a sequential one-pot bromination-aromatization-bromination of N-carbomethoxyindoline (2) is described. The process for the transformation of 2 into 6 permitted the isolation of stable reaction intermediates N-carbomethoxy-5-bromoindoline (3), N-carbomethoxy-5-bromoindole (4), and N-carbomethoxy-3,5-dibromoindole (5). Compound 6 was used to complete the total synthesis of the natural products 1b and 1c. In addition, bromination of N-carbomethoxyindole (11) afforded N-carbomethoxy-2,3,6-tribromoindole (13), from which the natural product 1a was synthesized.
