918529-91-6

Basic information

• Product Name: 1H-Indole-1-carboxylic acid, 5-bromo-2,3-dihydro-, methyl ester
• Synonyms: 1H-INDOLE-1-CARBOXYLIC ACID, 5-BROMO-2,3-DIHYDRO-, METHYL ESTER
• CAS NO: 918529-91-6
• Molecular Formula: C10H10BrNO2
• Molecular Weight: 256.099
• Mol File: 918529-91-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 337.4±41.0 °C (760 mmHg)
• Density: 1.567±0.06 g/cm3 (20 °C, 760 mmHg)
• CAS DataBase Reference: 1H-Indole-1-carboxylic acid, 5-bromo-2,3-dihydro-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-1-carboxylic acid, 5-bromo-2,3-dihydro-, methyl ester(918529-91-6)
• EPA Substance Registry System: 1H-Indole-1-carboxylic acid, 5-bromo-2,3-dihydro-, methyl ester(918529-91-6)

Safety Data

• Hazardous Substances Data: 918529-91-6(Hazardous Substances Data)

Upstream product

• 89875-37-6 2,3-dihydroindole-1-carboxylic acid methyl ester 

Downstream Products

• 10075-50-0 5-bromo-1H-indole 
• 81387-89-5 3,5-dibromo-1H-indole 

Relevant articles and documents

Green bromination method

The invention discloses a green bromination method, and belongs to the field of green organic chemistry. Under the conditions of room temperature, opening and neutrality, reaction raw materials are aromatic hydrocarbon, olefin, alkyne, tryptamine, tryptophane and derivatives thereof with different functional groups, a bromine source is MBrx (M is Fe , Fe , Ce and the like, and x is 2-3), and the unique oxidant is H2O2. Brominated alkanes, alkenes, aromatic hydrocarbons, pyrrolo-indolines and furo-indolines and derivatives thereof can be produced. The bromination reaction is carried out by using easily available and cheap reagents (such as FeBr2, CeB3 and H2O2) in the market and the solvent, and the method has the characteristics of mild reaction conditions, wide substrate application range, simple steps, easiness in operation and no need of separation, is a green, environment-friendly and safe bromination reaction method, and has a good application prospect.