81388-76-3

Basic information

• Product Name: 2-<<(p-chlorophenyl)selenenyl>methyl>-1-cyclohexanone
• CAS NO: 81388-76-3
• Molecular Weight: 301.675
• Mol File: 81388-76-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-<<(p-chlorophenyl)selenenyl>methyl>-1-cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<<(p-chlorophenyl)selenenyl>methyl>-1-cyclohexanone(81388-76-3)
• EPA Substance Registry System: 2-<<(p-chlorophenyl)selenenyl>methyl>-1-cyclohexanone(81388-76-3)

Safety Data

• Hazardous Substances Data: 81388-76-3(Hazardous Substances Data)

Upstream product

• 81388-77-4 6-(4-Chloro-phenylselanylmethyl)-1,4-dioxa-spiro[4.5]decane 
• 81388-75-2 1,4-dioxaspiro[4.5]dec-6-ylmethyl methanesulfonate 
• 20541-49-5 bis(p-chlorophenyl) diselenide 
• 23153-80-2 1,4-dioxaspiro[4.5]dec-6-yl-methanol 

Downstream Products

• 132591-61-8 5-<<(p-chlorophenyl)selenenyl>methyl>spiro<3.5>nonan-1-one 
• 81388-74-1 2-methyl-6-(2-methyl-1-cyclohexen-1-yl)-2-hexen-3-one 

Relevant articles and documents

Preparation and Rearrangement of 1,2-Dialkenylcyclobutanols. A Useful Method for Synthesis of Substituted Cyclooctenones

The syntheses and anionic oxy-Cope rearrangements of 1,2-dialkenylcyclobutanols are reported.Reaction of 2-methyl-2-(2-methylpropen-1-yl)-1-cyclobutanone (1) with vinyl-, isopropenyl-, or isobutenyllithium led to formation of cyclobutanols 2a-c.Treatment with potassium hydride induced rearrangement to Z and E cyclooctenones 3a-c and 4a,c.Reaction of 5-methylenespirononan-1-one (8) with the same alkenyllithium reagents afforded directly a mixture of rearranged and ring-opened products (11a-c and 12a-c).Reaction of spironon-5-en-1-one (17) with vinyl- or isopropenylmagnesium bromide produced a mixture of diastereomeric cyclobutanols 18a,b and 19a,b which underwent anionic oxy-Cope rearrangement to bicycloundec-1(11)-en-4-ones 20a,b in high yield.A mechanism for the rearrangement of stereodistal 1,2-dialkenylcyclobutanols is proposed.