81398-31-4

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-, (S)-
• CAS NO: 81398-31-4
• Molecular Formula: C15H12O7
• Molecular Weight: 304.256
• Mol File: 81398-31-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-, (S)-(81398-31-4)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-, (S)-(81398-31-4)

Safety Data

• Hazardous Substances Data: 81398-31-4(Hazardous Substances Data)

Upstream product

• 78708-33-5 plantagoside 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 65490-09-7 2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone 

Downstream Products

• 78335-36-1 2-(S)-5,7,3',4',5'-pentamethoxyflavanone 

Relevant articles and documents

Synthesis and biological evaluation of 5,7-dihydroxyflavanone derivatives as antimicrobial agents

A series of 5,7-dihydroxyflavanone derivatives were efficiently synthesized. Their antimicrobial efficacy on Gram-negative, Gram-positive bacteria and yeast were evaluated. Among these compounds, most of the halogenated derivatives exhibited the best antimicrobial activity against Gram-positive bacteria, the yeast Saccharomyces cerevisiae, and the Gram-negative bacterium Vibrio cholerae. The cytotoxicities of these compounds were low as evaluated on HepG2 cells using a cell viability assay. This study suggests that halogenated flavanones might represent promising pharmacological candidates for further drug development.