81398-31-4Relevant academic research and scientific papers
Synthesis and biological evaluation of 5,7-dihydroxyflavanone derivatives as antimicrobial agents
Zhang, Xing,Khalidi, Omar,Kim, So Young,Wang, Ruitong,Schultz, Victor,Cress, Brady F.,Gross, Richard A.,Koffas, Mattheos A.G.,Linhardt, Robert J.
, p. 3089 - 3092 (2016/06/13)
A series of 5,7-dihydroxyflavanone derivatives were efficiently synthesized. Their antimicrobial efficacy on Gram-negative, Gram-positive bacteria and yeast were evaluated. Among these compounds, most of the halogenated derivatives exhibited the best antimicrobial activity against Gram-positive bacteria, the yeast Saccharomyces cerevisiae, and the Gram-negative bacterium Vibrio cholerae. The cytotoxicities of these compounds were low as evaluated on HepG2 cells using a cell viability assay. This study suggests that halogenated flavanones might represent promising pharmacological candidates for further drug development.
THE GLYCOSIDES OF PLANTAGO MAJOR VAR. JAPONICA NAKAI. A NEW FLAVANONE GLYCOSIDE, PLANTAGOSIDE
Endo, Tohru,Taguchi, Heihachiro,Yosioka, Itiro
, p. 1000 - 1004 (2007/10/02)
A new flavanone glucoside, plantagoside (1) was isolated from the seeds of Plantago major var. japonica Nakai (Plantaginaceae) together with aucubin, geniposidic acid, acteoside and syringin.The structure of plantagoside was elucidated to be 1 on the basis of chemical and spectral evidence.Keywords-Plantago major var. japonica Nakai; Plantagoside; flavanone glucoside; aucubin; geniposidic acid; acteoside; syringin; 13C NMR
