81418-01-1

Basic information

• Product Name: 1-PYRIDIN-3-YL-PENT-4-EN-1-OL
• Synonyms: 1-PYRIDIN-3-YL-PENT-4-EN-1-OL
• CAS NO: 81418-01-1
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.22
• Mol File: 81418-01-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-PYRIDIN-3-YL-PENT-4-EN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PYRIDIN-3-YL-PENT-4-EN-1-OL(81418-01-1)
• EPA Substance Registry System: 1-PYRIDIN-3-YL-PENT-4-EN-1-OL(81418-01-1)

Safety Data

• Hazardous Substances Data: 81418-01-1(Hazardous Substances Data)

Usage

Structure

A pyridine ring attached to a five-carbon chain with a double bond The structure of 1-PYRIDIN-3-YL-PENT-4-EN-1-OL consists of a pyridine ring (a six-membered aromatic ring with one nitrogen atom) attached to a five-carbon chain containing a double bond.

Usage in pharmaceutical industry

Precursor or intermediate in the synthesis of various pharmaceutical compounds 1-PYRIDIN-3-YL-PENT-4-EN-1-OL is commonly used in the pharmaceutical industry as a precursor or intermediate in the synthesis of various pharmaceutical compounds.

Applications

Building block in the production of pharmaceutical drugs and in the creation of new molecules for drug discovery This chemical has a variety of applications, including as a building block in the production of pharmaceutical drugs and in the creation of new molecules for drug discovery.

Medicinal properties

Potential medicinal properties 1-PYRIDIN-3-YL-PENT-4-EN-1-OL is important for its potential medicinal properties and ability to be modified into various derivatives for therapeutic use.

Academic research and chemical synthesis

Unique structure and reactivity Additionally, it can be used in academic research and chemical synthesis due to its unique structure and reactivity.

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 7103-09-5 4-but-1-enylmagnesium bromide 
• 5162-44-7 1-bromo-4-butene 

Relevant articles and documents

Microwave-assisted telescoped cross metathesis-ring closing aza-Michael reaction sequence: step-economical access to nicotine-lobeline hybrid analogues

A series of 2,5-disubstituted pyrrolidines was synthesized through an efficient telescoped cross-metathesis/cyclizing aza-Michael addition involving N-heteroaromatic olefinic derivatives. This synthetic route was applied to the preparation of original nicotine-lobeline, nicotine-pelletierine and lobeline-nicotine-epibatidine hybrids.

Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries

The design, synthesis and decoration of six small molecule libraries is described. Each library was inspired by structures embedded in the framework of specific alkaloid natural products. The development of optimised syntheses of the required molecular scaffolds is described, in which reactions including Pd-catalysed aminoarylation and diplolar cycloadditions have been exploited as key steps. The synthesis of selected exemplar screening compounds is also described. In five cases, libraries were subsequently nominated for production on the basis of the scope and limitations of the validation work, as well as predicted molecular properties. In total, the research has led to the successful synthesis of >2500 novel alkaloid-like compounds for addition to the screening collection (the Joint European Compound Library, JECL) of the European Lead Factory.

Directed intermolecular carbomagnesation across vinylsilanes: 2-PyMe2Si group as a removable directing group

Facile addition of primary alkyl Gridnard reagents to vinylsilanes has been realized for the first time by exploiting the directing effect of a 2-pridyl group on silicon [Eq. (1)]. Three-component coupling reactions of a Grignard reagent, the vinylsilane,