81418-03-3

Basic information

• Product Name: 1-(3-Pyridinyl)-1-hexanone
• Synonyms: 1-(3-Pyridinyl)-1-hexanone;1-(pyridin-3-yl)hexan-1-one
• CAS NO: 81418-03-3
• Molecular Formula: C11H15NO
• Molecular Weight: 177.2429
• Mol File: 81418-03-3.mol

Chemical Properties

• Boiling Point: 286.5±13.0 °C(Predicted)
• Appearance: /
• Density: 0.983±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.24±0.10(Predicted)
• CAS DataBase Reference: 1-(3-Pyridinyl)-1-hexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Pyridinyl)-1-hexanone(81418-03-3)
• EPA Substance Registry System: 1-(3-Pyridinyl)-1-hexanone(81418-03-3)

Safety Data

• Hazardous Substances Data: 81418-03-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(3-Pyridinyl)-1-hexanone is used as a chemical intermediate for the production of nicotine derivatives and pharmaceuticals that target central nervous system disorders. Its unique structure allows for the development of compounds that can effectively address these conditions.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(3-Pyridinyl)-1-hexanone is used as a building block in the synthesis of insecticides and herbicides. Its ability to disrupt the biological processes of pests and weeds makes it a valuable component in creating effective solutions for agricultural challenges.
Used in Flavor and Fragrance Industry:
1-(3-Pyridinyl)-1-hexanone is also utilized in the preparation of flavor and fragrance compounds, making it an important chemical for the food and cosmetics industries. Its versatile structure enables the creation of a wide range of scents and flavors that can be used in various products.

Upstream product

• 614-18-6 3-pyridinecarboxylic acid ethyl ester 
• 23708-48-7 pentamethylenebis(magnesium bromide) 
• 500-22-1 3-pyridinecarboxaldehyde 
• 109-67-1 1-penten 
• 100-54-9 pyridine-3-carbonitrile 
• 110-53-2 1-Bromopentane 

Relevant articles and documents

Urea-Catalyzed Vinyl Carbocation Formation Enables Mild Functionalization of Unactivated C-H Bonds

Herein we report the 3,5-bistrifluoromethylphenyl urea-catalyzed functionalization of unactivated C-H bonds. In this system, the urea catalyst mediates the formation of high-energy vinyl carbocations that undergo facile C-H insertion and Friedel-Crafts re

Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives

Hydroacylation of 1-alkene with a heteroaromatic aldehyde such as pyridinecarboxaldehyde, thiophenecarboxaldehyde and furfural derivatives under cocatalyst of Wilkinson's complex and 2-amino-3-picoline gave poor yield of hydroacylated product. The addition of a catalytic amount of bis(cyclopentadienyl)zirconium dichloride or bis(cyclopentadienyl)titanium dichloride as an additive dramatically increased the yield of the hydroacylated ketone product.

STERIC EFFECTS IN THE REACTION OF DI(BROMOMAGNESIO)ALKANES WITH CARBOXYLIC ESTERS

Largely different product distributions were observed on the action of various carboxylic esters with 1,4-di(bromomagnesio)butane and its homologue 1,5-di(bromomagnesio)pentane.The much larger yields of reduction product with the latter are the evidence for the structural geometric requirements for the annelation step.