81420-05-5Relevant academic research and scientific papers
Palladium-Catalyzed Regio- and Stereoselective Hydrosulfonation of Propiolate Esters
Raju, Selvam,Annamalai, Pratheepkumar,Chan, Fu-Wei,Tseng, Po-Yen,Chen, Po-Yen,Kuo, Ting-Shen,Chuang, Shih-Ching
, p. 5007 - 5016 (2017)
An efficient palladium-catalyzed addition reaction of alkyl- and arylsulfonic acids to propiolate esters to yield alkenyl sulfonates is demonstrated. The formation of alkenyl sulfonates is highly regio- and stereoselective with favorable yields of up to 95%, and two of the alkenyl sulfonates are utilized for a Sonogashira cross-coupling reaction to produce (Z)-1,3-enynoates.
