81427-15-8

Basic information

• Product Name: hazaleamide
• Synonyms: hazaleamide
• CAS NO: 81427-15-8
• Molecular Formula: C18H29NO
• Molecular Weight: 275.42896
• Mol File: 81427-15-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 440.9°Cat760mmHg
• Flash Point: 271.8°C
• Appearance: /
• Density: 0.898g/cm³
• Vapor Pressure: 5.68E-08mmHg at 25°C
• Refractive Index: 1.494
• CAS DataBase Reference: hazaleamide(CAS DataBase Reference)
• NIST Chemistry Reference: hazaleamide(81427-15-8)
• EPA Substance Registry System: hazaleamide(81427-15-8)

Safety Data

• Hazardous Substances Data: 81427-15-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C18H29NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-18(20)19-16-17(2)3/h5-6,8-9,12-15,17H,4,7,10-11,16H2,1-3H3,(H,19,20)/b6-5-,9-8-,13-12+,15-14+

Upstream product

• 78-81-9 isobutylamine 
• 63478-76-2 1-hydroxy-6-heptyne 
• 37011-86-2 tetrahydro-2-(6-heptynyloxy)-2H-pyran 
• 21662-12-4 (6Z,9Z)-dodeca-6,9-dienal 

Relevant articles and documents

Synthesis of Bungeanool, Isobungeanool, Dihydrobungeanool, Tetrahydrobungeanool, Hazaleamide, Lanyuamide III, and Analogues

The bungeanools are a family of alkamide natural products isolated from the pericarps of Zanthoxylum bungeanum (Sichuan pepper), and they are structurally related to the sanshools. While the sanshools, especially hydroxy-?-sanshool, have been studied in a variety of contexts, research regarding the bungeanools has been much more limited. To facilitate their study, we have developed stereoselective syntheses of all four members of this family of compounds by using flexible routes that are also amenable to the synthesis of analogues. The key transformation in the syntheses was the stereoselective triphenylphosphine/ phenol-catalyzed isomerization of an alkynoate to the corresponding conjugated E,E-dienoate.