81428-57-1Relevant articles and documents
Unexpected Behaviour of 2-Bromoethyl 4-Hydroxybenzoate with Sodium Hydroxide
Nonnenmacher, Alex,Plieninger, Hans
, p. 1244 - 1246 (2007/10/02)
Whereas 2-bromoethyl benzoate hydrolyzes quickly with sodium hydroxide to yield benzoic acid, 2-bromoethyl 4-hydroxybenzoate (1) with equimolar amounts of sodium hydroxide gives quantitatively 2-hydroxyethyl 4-hydroxybenzoate (6).It is proved with deuterated compounds that this reaction proceeds with internal C = O alkylation via the intermediate 5.