81435-41-8Relevant academic research and scientific papers
Nucleophilic reactions of propargyl acetates mediated by titanocene dichloride and magnesium
Yang, Fanglong,Zhao, Gang,Ding, Yu
, p. 2839 - 2841 (2007/10/03)
Reaction of Cp2TiCl2/Mg with propargyl acetates form allenyl titanium intermediates, which undergo nucleophilic addition reactions to aldehydes or ketones to give homopropargyl alcohols in high yields. Subsequent nucleophilic additio
Regio- and Stereocontrolled Synthesis of Allenic and Acetylenic Derivatives. Organotitanium and Boron Reagents
Furuta, Kyoji,Ishiguro, Masaharu,Haruta, Ryuichi,Ikeda, Nobuo,Yamamoto, Hisashi
, p. 2768 - 2776 (2007/10/02)
The propargyltitanium reagents derived from 1-alkylpropyne condensed with aldehydes to give α-allenyl alcohol regioselectively, while the allenyltitanium reagents generated from 1-alkyl-1-butyne derivatives gave threo-β-acetylenic alcohols with high regio- and stereoselectivities.The course of the reaction was determined by the substitution pattern of starting alkynes.The similar reactions of metallated 1,3-bis(trialkylsilyl)propyne or (trialkylsilyl)acetonitrile with aldehydes were also investigated.
Propargylic Titanium Reagents. Regio- and Stereocontrolled Synthesis of Allenic and Acetylenic Alcohols
Ishiguro, Masaharu,Yamamoto, Nobuo Ikeda Hisashi
, p. 2225 - 2227 (2007/10/02)
The highly selective condensations of propargylic titanium reagents and aldehydes are described.
