81444-73-7

Basic information

• Product Name: N-(benzyloxycarbonyl)-D-tryptophanyl-L-tryptophan methyl ester
• Synonyms: N-(benzyloxycarbonyl)-D-tryptophanyl-L-tryptophan methyl ester
• CAS NO: 81444-73-7
• Molecular Weight: 538.603
• Mol File: 81444-73-7.mol

Chemical Properties

• CAS DataBase Reference: N-(benzyloxycarbonyl)-D-tryptophanyl-L-tryptophan methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzyloxycarbonyl)-D-tryptophanyl-L-tryptophan methyl ester(81444-73-7)
• EPA Substance Registry System: N-(benzyloxycarbonyl)-D-tryptophanyl-L-tryptophan methyl ester(81444-73-7)

Safety Data

• Hazardous Substances Data: 81444-73-7(Hazardous Substances Data)

Upstream product

• 4299-70-1 L-tryptophan methyl ester 
• 2279-15-4 N-(benzyloxycarbonyl)-D-tryptophan 
• 7524-52-9 (S)-tryptophan methyl ester hydrochloride 

Downstream Products

• 82989-14-8 Z-(D)-Trp-(L)-Trp-(L)-Pro-PNP 
• 82989-10-4 Z-(D)-Trp-(L)-Trp(COOH) 

Relevant articles and documents

Ground- and Excited-State Conformational Differences between Diastereomeric Dipeptides

Ground- and excited-state conformations of D-tryptophanyl-L-tryptophan methyl ester (1DL) L-tryptophanyl-L-tryptophan methyl ester (1LL) have been investigated by 1H NMR and by steady-state and subnanosecond time-resolved fluorescenc

TREATMENT OF PROTEIN FOLDING DISORDERS

In certain embodiments, the invention is directed to a method for treating a protein folding disorder such as Alzheimer's disease, dementia, Parkinson's disease, Huntington's disease and prion-based spongiform encephalopathy. The method comprises the administration to a subject of a compound of the formula (I) wherein A and B are independently a mono- or bicyclic aromatic group or heteroaromatic cyclic group. In preferred embodiments, the compounds are bis-indole compounds.

STEREOSELECTIVITY IN MICELLAR AND VESICULAR REACTIONS

The diastereoselectivity of esterolytic cleavage of certain dipeptide and tripeptide activated esters is lower in thio-functionalized vesicles than in comparable micelles.This is thought to be a mechanism-specific effect related to the greater molecular o