81456-94-2

Upstream product

• 90974-65-5 1-hydroxymethyl-3,3,4-trimethyl-1-cyclohexene 
• 1502-24-5 2,3-dimethylcyclohexan-1-ol 
• 13395-76-1 2,3-dimethylcyclohexanone 
• 526-75-0 2,3-Dimethylphenol 
• 535-11-5 Ethyl 2-bromopropionate 

Downstream Products

• 6138-84-7 (+)-1-((1Ξ)-2,2,3c,6c-tetramethyl-cyclohexyl-(r))-butanone-(3) 

Relevant academic research and scientific papers

Syntheses of (+/-)-cis γ-Irone and Its Related Compounds

(+/-)-cis-γ-Irone (1a), (+/-)-cis-dihydro-γ-irone (2a) and their trans-isomers (1b, 2b) were synthesized via 3,3-(Claisen) or 2,3-sigmatropic rearrangement of 1-hydroxymethyl-3,3,4-trimethyl-1-cyclohexene (8) derivatives as each key step.

Irigermanal and Iridogermanal: Two New Triterpenoids from Rhizomes of Iris germanica L.

α-Irigermanal (8a), γ-irigermanal (8b), and iridogermanal (12) are the major extractable lipids of the rhizomes of Iris germanica, constituting about 1percent of their fresh weight.The structure of the compounds was determined by detailed spectral analysis, chemical degradation, and X-ray crystallography. 8b crystallizes as a methanol solvate in the space group P21 with a = 13.05 (1) Angstroem, b = 8.84 (2) Angstroem, c = 13.78 (1) Angstroem, β = 105.84 (5) deg, and Z = 2.The irigermanals are the first known bicyclic triterpenoids, and iridogermanal is the firstmonocyclic triterpenoid found so far.The compounds are closely related to ambreine.