81462-29-5

Upstream product

• 60734-30-7 cis-3-(o-anisyl)-4-methoxycarbonyl-2-methyl-3,4-dihydro-1(2H)-isoquinolone 
• 60734-30-7 methyl trans-3(2-methoxyphenyl)-2-methyl-3,4-dihydro-1(2H)-isoquinoline-4-carboxylate 

Downstream Products

• 76694-23-0 trans-4-hydroxymethyl-3-(o-methoxyphenyl)-N-methyl-1,2,3,4-tetrahydro-isoquinoline 
• 81462-30-8 trans-4-acetoxymethyl-3-(o-methoxyphenyl)-N-methyl-3,4-dihydro-1(2H)-isoquinolone 

Relevant academic research and scientific papers

Carbon-13 NMR Studies: Effect of Steric Compression on Chemical Shifts of Carbon Atoms in the Heterocyclic Ring of Substituted 1,2,3,4-Tetrahydroisoquinolines

Comparative 13C NMR spectra of 1,2,3,4-tetrasubstituted and 1,2-disubstituted 1,2,3,4-tetrahydroisoquinolines reveal the effect of steric compression on the chemical shifts of C-1, C-3 and C-4 carbon atoms in the heterocyclic ring of substituted 1,2,3,4-t

Retention of Ring Configuration During Hydride Reduction of 4-Methoxycarbonyl-3,4-dihydro-1(2H)-isoquinolone Derivatives

Retention of the ring configuration during the reduction of cis- and trans-methyl esters of 3-(o-anisyl)-4-carboxy-2-methyl-3,4-dihydro-1(2H)-isoquinolone with LiBH4 and LiAlH4 has been studied.It has been observed that the thermodynamic stability of the cis- and trans-isomers and their intermediates formed during the reaction influences the stereochemistry of the products obtained after reduction.

Acylation of Alcohols by Fatty Acid Esters in Presence of Lithium Aluminium Hydride

A novel acylation of alcohols by fatty acid esters in the presence of lithium aluminium hydride is reported.A plausible mechanism of this acylation through the formation of a lithium aluminium tetraalkoxide complex has been suggested.