81478-01-5Relevant academic research and scientific papers
Selective Alkylation of Protected Peptide Derivatives by Phase-transfer Catalysis
O'Donnell, M.J.,Burkholder, T.P.,Khau, V.V.,Roeske, R.W.,Tian, Z.
, p. 2477 - 2488 (2007/10/02)
Schiff base dipeptide esters are selectively alkylated at the N-terminal α-carbon by phase-transfer catalysis to give both diastereomeric products.The reaction occurs with retention of configuration at the C-terminal α-carbon containing a non-glycine resi
