81482-46-4

Upstream product

• 82997-96-4 (R)-3-(1-Methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-7-[(E)-trifluoromethanesulfonylimino]-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 53090-86-1 7β-amino-3-<<(1-methyl-1H-tetrazol-5-yl)thio>methyl>ceph-3-em-4-oic acid benzhydryl ester 
• 81482-44-2 C₂₅H₂₀F₆N₆O₇S₄ 

Downstream Products

• 84048-61-3 Diphenylmethyl 7-methoxyimino-3-(1-methyl-1H-tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylate 
• 81482-72-6 (R)-7-(tert-Butoxycarbonyl-hydrazono)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 81482-71-5 Diphenylmethyl (E)-7-t-butoxycarbonylhydrazono-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate 
• 84048-59-9 Diphenylmethyl 7-hydroxyimino-3-(1-methyl-1H-tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylate 
• 81482-81-7 (6R,7R)-7-(N'-tert-Butoxycarbonyl-hydrazino)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 82975-17-5 (6R,7R)-7-[N'-tert-Butoxycarbonyl-N-(2-thiophen-2-yl-acetyl)-hydrazino]-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 81482-75-9 (6R,7R)-7-Methoxyamino-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 81482-89-5 (6R,7R)-7-[Methoxy-(2-thiophen-2-yl-acetyl)-amino]-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 

Relevant academic research and scientific papers

Method of producing oxo-containing azetidinone compounds

This invention relates to a novel method of producing oxo-containing azetidinone compounds, or salts thereof, or hydrates thereof, said compounds having utility as antimicrobial agents and as intermediates for the synthesis of other azetidinone compounds having antimicrobial activity.

An Efficient Synthesis of 6-Oxopenicillanic and 7-Oxocephalosporanic Acid Derivatives

Trifluoromethanesulphonation of benzyl 6-aminopenicillanate (3) and the 7-aminocephalosporanates (7a-c) with (CF3SO2)2O gave the bis(trifluoromethylsulphonate) derivatives (5) and (8a-c), which were then converted into the imines (6) and (9a-c) by treatme