81485-25-8Relevant articles and documents
Method for preparing french Nepal aldehydeaccompanies the Swiss Uygur A and method for the preparation of acid
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, (2017/04/05)
The invention provides a preparation method for Fanny aldehyde. The method comprises the step of performing an oxidizing reaction on farnesol under the effects of a catalyst and an oxidizing agent in an organic solvent to obtain the Fanny aldehyde, wherein the catalyst is Cu (copper) or a cupric compound. The invention further provides a preparation method for peretinoin. By the method disclosed by the invention, the metallic copper or the cupric compound are used as the catalyst to catalyze farnesol into the Fanny aldehyde, so that not only is the catalytic efficiency higher and the reaction conditions are mild, but also the purity and the yield of the prepared Fanny aldehyde are higher, and the Fanny aldehyde can be directly used for subsequently preparing the peretinoin without being purified. In addition, the preparation method for the Fanny aldehyde disclosed by the invention is green and pollution-free, and the industrial production can be realized. Experiment results prove that the yield of the Fanny aldehyde prepared by the method provided by the invention is more than 85%, and the purity is more than 95%; experiment results prove that the purity of a crude product of the peretinoin prepared by the method provided by the invention is more than 98%, and the purity is more than 99% after the crude product is recrystallized and refined.
Method for preparing polyprenyl compounds
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, (2008/06/13)
A method for preparing a polyprenyl compound wherein an aldehyde represented by the following general formula [I]: [wherein n represents an integer of from 0 to 3] and a Wittig reagent represented by the following general formula [II]: [wherein each of R1 and R2 represents a group consisting of hydrocarbon] are reacted in a medium as a mixture of water and an organic solvent in the presence of a base, and further in the presence of a crown ether. Said method achieves an excellent selectivity and a high yield.
3,7,11,15-Tetramethyl-2,4,6,10,14,-hexadecapentaendic acid
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, (2008/06/13)
A novel compound, 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid, and a salt thereof are disclosed together with a number of different processes for the preparation of the compound. The uses of the novel compound as an anticancer agent are also disclosed.