81494-04-4 Usage
Description
2-Chloro-N-(2-methoxy-benzyl)-acetamide is a chemical compound with the molecular formula C10H12ClNO2. It is an organic compound characterized by the presence of a chloride and a carbonyl functional group, along with a benzyl and a methoxy group. 2-Chloro-N-(2-methoxy-benzyl)-acetamide is recognized for its role as a building block in the pharmaceutical industry and for its applications in organic synthesis.
Uses
Used in Pharmaceutical Industry:
2-Chloro-N-(2-methoxy-benzyl)-acetamide is used as an intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs. Its unique structure allows it to be a valuable component in creating a variety of medicinal compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Chloro-N-(2-methoxy-benzyl)-acetamide is utilized as a key intermediate. Its functional groups enable it to participate in various chemical reactions, facilitating the creation of a wide range of organic compounds for different applications.
It is crucial to handle 2-Chloro-N-(2-methoxy-benzyl)-acetamide with care and adhere to safety protocols during its use in chemical processes to ensure the safety of both individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 81494-04-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,4,9 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 81494-04:
(7*8)+(6*1)+(5*4)+(4*9)+(3*4)+(2*0)+(1*4)=134
134 % 10 = 4
So 81494-04-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H12ClNO2/c1-14-9-5-3-2-4-8(9)7-12-10(13)6-11/h2-5H,6-7H2,1H3,(H,12,13)
81494-04-4Relevant articles and documents
Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptor
Huynh, Tracey,Valant, Celine,Crosby, Ian T.,Sexton, Patrick M.,Christopoulos, Arthur,Capuano, Ben
, p. 8196 - 8200 (2013/11/06)
The M4 mAChR is implicated in several CNS disorders and possesses an allosteric binding site for which ligands modulating the affinity and/or efficacy of ACh may be exploited for selective receptor targeting. We report the synthesis of a focused library of putative M4 PAMs derived from VU0152100 and VU10005. These compounds investigate the pharmacological effects of previously identified methoxy and fluoro substituents, providing useful estimates of affinity (KB), cooperativity (αβ), and direct agonist properties (τB).