81500-92-7

Usage

Uses

Used in Organic Synthesis:
3,5-Bis(trimethylsilyl)bromobenzene is used as a reagent in organic synthesis for its ability to facilitate the formation of carbon-carbon and carbon-heteroatom bonds. This function is crucial in the construction of complex organic molecules, where it serves as a versatile building block.
Used in Cross-Coupling Reactions:
In the field of cross-coupling reactions, 3,5-Bis(trimethylsilyl)bromobenzene is utilized as a key component to promote the formation of new carbon-carbon bonds. Its presence ensures efficient and controlled reactions, which is essential for the synthesis of a wide range of organic compounds.
Used in the Pharmaceutical Industry:
3,5-Bis(trimethylsilyl)bromobenzene is employed in the pharmaceutical industry as a precursor for the synthesis of various pharmaceutical compounds. Its reactivity and selectivity make it a valuable tool in the development of new drugs and medicinal agents.
Used in the Chemical Industry:
In the chemical industry, 3,5-Bis(trimethylsilyl)bromobenzene is used as an intermediate in the production of specialty chemicals, including agrochemicals, dyes, and other organic compounds. Its unique properties allow for the synthesis of a diverse range of products with specific applications.
Used in Material Science:
3,5-Bis(trimethylsilyl)bromobenzene is also utilized in material science for the development of new materials with unique properties. Its ability to form stable bonds with various atoms makes it a promising candidate for the synthesis of advanced materials with potential applications in electronics, coatings, and other industries.

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 626-39-1 1,3,5-trisbromobenzene 
• 507-20-0 tertiary butyl chloride 

Downstream Products

• 528577-35-7 1,3-bis(trimethylsilyl)-5-(3,3-dimethoxypropyl)benzene 
• 149428-64-8 1-bromo-3,5-diiodobenzene 
• 1620166-10-0 C₆₂H₉₂O₆P₂Si₈ 
• 1203710-21-7 1,2-{bis[3,5-bis(trimethylsilyl)pheny]phosphino}benzene 
• 528577-20-0 1-(2-benzyloxyethyl)-3,5-bis(trimethylsilyl)benzene 
• 528577-21-1 1-(2-benzyloxyethyl)-3,5-diiodobenzene 
• 528577-38-0 1-but-3-enyl-3,5-diiodobenzene 
• 528577-37-9 3-(3,5-diiodophenyl)propionaldehyde 
• 676259-30-6 1,3,5-tris[3-(3,5-bis(trimethylsilyl)phenyl)propyl]benzene 
• 676259-36-2 2-{3,5-bis[3-(4-trimethylsilylphenyl)propyl]phenyl}-4,4,5,5-tetramethyl[1,3,2]dioxaborane 
• 676259-35-1 1-bromo-3,5-bis-[3-[4-(trimethylsilyl)phenyl]propyl]benzene 
• 634598-10-0 2-{4-{3-[3,5-bis(trimethylsilyl)phenyl]propyl}phenyl}-4,4,5,5-tetramethyl-[1,3,2]-dioxaborane 
• 676259-32-8 C₂₁H₃₃BO₂Si₂ 
• 634598-11-1 2-{4-[3-(3,5-diiodophenyl)propyl]phenyl}-4,4,5,5-tetramethyl[1,3,2]dioxaborane 

Relevant academic research and scientific papers

Linear Hydroaminoalkylation Products from Alkyl-Substituted Alkenes

The regioselective conversion of alkyl-substituted alkenes into linear hydroaminoalkylation products represents a strongly desirable synthetic transformation. In particular, such conversions of N-methylamine derivatives are of great scientific interest, because they would give direct access to important amines with unbranched alkyl chains. Herein, we present a new one-pot procedure that includes an initial alkene hydroaminoalkylation with an α-silylated amine substrate and a subsequent protodesilylation reaction that delivers linear hydroaminoalkylation products with high selectivity from simple alkyl-substituted alkenes. For that purpose, new titanium catalysts have been developed, which are able to activate the α-C?H bond of more challenging α-silylated amine substrates. In addition, a direct relationship between the ligand structure of the new catalysts and the obtained regioselectivity is described.

2-AMINO SUBSTITUTED PYRIDINE DERIVATIVE

PROBLEM TO BE SOLVED: To provide a 2-amino substituted pyridine derivative useful as an active ingredient of medicines such as antipsychotic agent, anti-anxiety agent, or brain function improver. SOLUTION: The present invention provides a compound represe

Iridium-catalyzed oxidative olefination of furans with unactivated alkenes

The oxidative coupling of arenes and alkenes is an attractive strategy for the synthesis of vinylarenes, but reactions with unactivated alkenes have typically occurred in low yield. We report an Ir-catalyzed oxidative coupling of furans with unactivated olefins to generate branched vinylfuran products in high yields and with high selectivities with a second alkene as the hydrogen acceptor. Detailed mechanistic experiments revealed catalyst decomposition pathways that were alleviated by the judicious selection of reaction conditions and application of new ligands.

LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS

A ligand useful to form a metallocene olefin polymerization catalyst comprises:wherein at least R3 and R4 are substituents having at least a bulk of a t-butyl group and, optionally, wherein R1 or R2 may be a bulky substituent group.

"AB2 + AC2" approach to hyperbranched polymers with a high degree of branching

A novel one-pot "AB2 + AC2" approach based on palladium catalyzed Suzuki polycondensation was developed to prepare hyperbranched aryl/alkyl polymers with a high degree of branching.

Synthesis of low generation phenylenealkylene dendrons as nonpolar building blocks for a dendrimer construction set

The gram scale syntheses of first and second generation (G1 and G2) dendrons 1-4, and 35, based on aryl and alkyl moieties, by Suzuki-Miyaura cross-coupling are presented. Both a divergent and an accelerated convergent route are applied. In addition, first results on the synthesis of hyperbranched oligomers of AB2 monomer 19 are reported.

ACETYLCHOLINESTERASE INHIBITORS

This invention relates to silylated aromatic fluoroketones possessing acetylcholinesterase-inhibiting properties and to their use in the treatment of Alzheimer disease and senile dementia

SILA-SUBSTITUTED PERFUMES. IV. SILA DERIVATIVES OF SOME MUSK SCENTS

The sila derivatives XII and XIII and the germa derivative XIV of the artificial musk scents 3,5-di(tert.butyl)benzaldehyde (A) and 3,5-di(tert.butyl)acetophenone (B) as well as the sila and germa derivatives XVIII and XIX of the "xylene musk" scent C, 2,