81527-04-0

Basic information

• Product Name: 1H-Imidazole, 4,5-bis(4-methoxyphenyl)-2-(2-thienylthio)-
• CAS NO: 81527-04-0
• Molecular Formula: C21H18N2O2S2
• Molecular Weight: 394.518
• Mol File: 81527-04-0.mol

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 4,5-bis(4-methoxyphenyl)-2-(2-thienylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 4,5-bis(4-methoxyphenyl)-2-(2-thienylthio)-(81527-04-0)
• EPA Substance Registry System: 1H-Imidazole, 4,5-bis(4-methoxyphenyl)-2-(2-thienylthio)-(81527-04-0)

Safety Data

• Hazardous Substances Data: 81527-04-0(Hazardous Substances Data)

Usage

Heterocyclic organic compound

A compound containing a ring structure with at least one ring atom being a heteroatom (an atom other than carbon), in this case, nitrogen.

Used in medicinal chemistry and drug discovery

The compound has potential applications in the development of new drugs and therapeutic agents due to its biological activities.

Antifungal

Capable of inhibiting or destroying fungi.

Antibacterial

Capable of inhibiting or destroying bacteria.

Antioxidant

Capable of neutralizing or reducing the effects of oxidation, which can cause cellular damage.

Valuable building block for the synthesis of pharmaceuticals and bioactive compounds

The unique structure and reactivity of the compound make it useful in creating new drugs and other biologically active substances.

Aromatic and substituted phenyl rings

The presence of aromatic (stable, unsaturated) rings and substituted (with other functional groups) phenyl rings contributes to the compound's potential applications in various fields of chemical research and development.

Upstream product

• 3437-95-4 2-Iodothiophene 
• 39908-69-5 4,5-bis(4-methoxyphenyl)-2-mercapto-1H-imidazole 
• 119-52-8 4,4'-dimethoxybenzoin 

Relevant articles and documents

METHOD OF USING (H+/K+)ATPASE INHIBITORS AS ANTIVIRAL AGENTS

A class of compounds which are (H+/K+) ATPase inhibitors can be used for the treatment of viral infections. Compounds of particular interest are defined by Formula III: wherein D is N or CH; wherein R7 is one or more radicals selected from hydrido, alkoxy, amino, cyano, nitro, hydroxyl, alkyl, halo, haloalkyl, carboxyl, alkanoyl, nitro, amino, alkylamino, aminocarbonyl , aminosulfonyl , alkylaminocarbonyl, alkylcarbonylamino, alkoxycarbonyl, alkylaminosulfonyl, alkylsulfonylamino, alkylthio, alkyl-sulfinyl and alkylsulfonyl; wherein R8 is selected from hydrido, alkyl and cycloalkyl; wherein R9 is one or more radicals selected from hydrido, alkoxy, amino, alkyl, halo, cyano, nitro, hydroxyl, haloalkyl, nitro, carboxyl, alkanoyl, amino, alkylamino, dialkylamino, aminocarbonyl , alkylaminocarbonyl, alkylcarbonylamino, aminosulfonyl, alkylaminosulfonyl, alkylsulfonylamino, alkoxycarbonyl, alkylthio, alkylsulfinyl and alkylsulfonyl; and wherein R10 and R11 are independently selected from hydrido, alkyl, aryl, alkylcarbonyl and arylcarbonyl wherein the aryl ring may be further substituted with one or more radicals selected from alkyl, halo, hydrazidylcarbonyl, aminocarbonyl and alkoxy; or wherein R10 and R11 together with the nitrogen atom form a heterocyclic ring

Antiinflammatory agents, XVII: 4,5-Bis-(4-methoxyphenyl)-2-(arylthio)azoles with antiinflammatory activity

The syntheses of 4,5-bis(4-methoxyphenyl)-2-(arylthio)imidazoles, -thiazoles and -oxazoles are described and their inflammatory activities are compared. Thioethers, sulfoxides, and sulfones of the phenyl, 4-fluorophenyl, and 2-thienyl derivatives were inv