81534-59-0

Basic information

• Product Name: 4,5-anti-5,6-O-isopropylidene-4,5,6-trihydroxy-1,1-dimethoxyhexan-2-one
• CAS NO: 81534-59-0
• Molecular Weight: 248.276
• Mol File: 81534-59-0.mol

Chemical Properties

• CAS DataBase Reference: 4,5-anti-5,6-O-isopropylidene-4,5,6-trihydroxy-1,1-dimethoxyhexan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-anti-5,6-O-isopropylidene-4,5,6-trihydroxy-1,1-dimethoxyhexan-2-one(81534-59-0)
• EPA Substance Registry System: 4,5-anti-5,6-O-isopropylidene-4,5,6-trihydroxy-1,1-dimethoxyhexan-2-one(81534-59-0)

Safety Data

• Hazardous Substances Data: 81534-59-0(Hazardous Substances Data)

Upstream product

• 6342-56-9 Pyruvic aldehyde dimethyl acetal 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Downstream Products

• 81534-61-4 (1S,3S)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-4,4-dimethoxy-butane-1,3-diol 
• 81534-60-3 (1S,3R)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-4,4-dimethoxy-butane-1,3-diol 

Relevant articles and documents

STEREOSELECTIVE REDUCTION OF β-HYDROXYKETONES TO 1,3-DIOLS. HIGHLY SELECTIVE 1,3-ASYMMETRIC INDUCTION VIA BORON CHELATES

Highly selective asymmetric induction can be achieved in the reduction of acyclic β-hydroxyketones via boron chelates.Treatment of β-hydroxyketones (1) with tributyl or triisobutylborane and successively with sodium borohydride afforded syn-1,3-diols (3)

Proline organocatalysis as a new tool for the asymmetric synthesis of ulosonic acid precursors

PEP and aldolase mimicry is the key for a direct organocatalytic entry to precursors of ulosonic acids, biomolecules of enormous importance in biology, chemistry and medicine; in the key aldol reaction the dimethylacetal of pyruvic aldehyde is used as pho

Direct aldol reaction of pyruvic derivatives: Catalytic attempt to synthesize ulosonic acids

The catalytic asymmetric aldol reaction of pyruvic aldehyde dimethyl acetal and 2-acetylthiazole with sugar aldehydes is demonstrated to be the key step in the synthesis of 3-deoxy-2-ulosonic acids. Efficient and stereoselective pyruvate aldol reactions are catalyzed by metal-based chiral Trost and Shibasaki catalysts. The presented synthetic methodology mimics aldolase-catalyzed reactions by direct activation of C3 pyruvate equivalents with the use of metal-based chiral catalysts en route to the synthesis of 2-keto-3-deoxy-D-glucosonic acid and 3-deoxy-D-manno-2-octulosonic acid derivatives. Copyright