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α-(2,6-diethyl-8-methylbenzo[1,2-d:4,5-d']bis(oxazol)-4-yl)-α-methylbenzyl alcohol is a complex organic compound characterized by its unique molecular structure. It features a benzene ring with two oxazole rings fused to it, creating a bis(oxazol) system. The benzene ring is substituted with a 2,6-diethyl and an 8-methyl group, which contribute to its steric and electronic properties. The α-methylbenzyl alcohol moiety, attached to the α-carbon of the molecule, introduces a hydroxyl group and a methyl group, enhancing its reactivity and solubility. α-(2,6-diethyl-8-methylbenzo<1,2-d:4,5-d'>bis(oxazol)-4-yl)-α-methylbenzyl alcohol is of interest in the field of organic chemistry, potentially for its applications in the synthesis of pharmaceuticals or materials science, due to its intricate structure and the possibility of forming stable complexes with various metal ions.

81553-80-2

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81553-80-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 81553-80-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,5,5 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 81553-80:
(7*8)+(6*1)+(5*5)+(4*5)+(3*3)+(2*8)+(1*0)=132
132 % 10 = 2
So 81553-80-2 is a valid CAS Registry Number.

81553-80-2Downstream Products

81553-80-2Relevant academic research and scientific papers

Synthesis of 2,5-Disubstituted 3,6-Diamino-1,4-benzoquinones

Hegedus, Louis S.,Odle, Roy R.,Winton, Peter M.,Weider, Paul R.

, p. 2607 - 2613 (2007/10/02)

A general synthetic approach to a wide variety of 2,5-disubstituted 3,6-diamino-1,4-benzoquinones was developed.Bromanil was diaminated with ammonia, and adjacent NH2 and OH groups were protected as benzoxazoles by treatment with a carboxylic acid chloride followed by a polyphosphate ester cyclization-dehydration.The resulting 2,5-dibromobenzobis(oxazoles) were monolithiated by halogen-metal exchange with n-butyllithium and then reacted with a variety of electrophiles.The remaining bromide was replaced in a similar fashion.Alternatively the second bromide was replaced by reaction with ? allylnickel halide complexes.The benzoxazole protecting group could be hydrolyzed with zinc(II) chloride/HCl-aqueous ethanol under an inert atmostphere.Air oxidation of the resulting hydroquinone under neutral conditions gave the desired 2,5-disubstituted 3,6-diamino-1,4-benzoquinone in good to excellent overall yield.This method was used to synthesize precursors to the basic ring system of the mitomycin antineoplastic antibiotics.Acid hydrolysis of the benzoxazole protecting group under oxidizing conditions resulted in the production of 2,5-disubstituted 3,6-dihydroxy-1,4-benzoquinone.Methylation followed by reaction with ammonia gave the desired diaminoquinone.

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