81555-08-0

Upstream product

• 50-00-0 formaldehyd 
• 154-23-4 catechin 
• 1599460-40-8 bis(3,5,7,3',4'-Penta-O-benzyl-8-catechinyl)methane 
• 89385-18-2 3,5,7,3',4'-penta-O-benzyl-8-formylcatechin 

Relevant academic research and scientific papers

Asymmetric total synthesis of talienbisflavan A

The first asymmetric total syntheses of talienbisflavan A and bis-8,8′-epicatechinylmethane as well as a facile synthesis of bis-8,8′-catechinylmethane has been accomplished from readily available starting materials by using a newly developed direct regio

Kinetics of Polymerization of (+)-Catechin with Formaldehyde

Rates of methylolation and condensation of (+)-catechin (1) with formaldehyde (2) in aqueous solution were measured over the pH range 6-9 and the temperature range 10-85 deg C.First-order kinetics were observed for the rates of disappearance of 1 and 2 as

Experimental and theoretical investigation of inhibition behavior of bisflavanol for Q235 steel in hydrochloric acid solution

Bis-8,8′-catechinylmethane, known as bisflavanol (BF), from cacao liquor was synthesized here as effective, eco-friendly, especially edible corrosion inhibitor for Q235 steel in HCl. The result of gravimetric measurements showed that the inhibition efficiency of BF at 0.1 mM was 92.42%, while catechin at 0.2 mM was 78.28%, reflecting a synergistic effect between the two catechin moieties of BF. Activation parameters ΔG0 ads, Ea, ΔH* and ΔS* were evaluated and discussed. Surface morphological analyses (SEM, EDX and AFM) showed that a film of inhibitor was formed on the surface of Q235 steel. XPS, Fukui function and MD simulations were used to study the corrosion inhibition performance of FP in HCl, predict the interaction between FP and Q235 steel, and verify the experimental results.

Synthesis of Bisflavanol-Type Natural Products and Their Analogues via Self-Coupling of C8-Methylol Catechin Derivatives

A highly efficient and regioselective self-coupling of C8-methylol catechin derivatives is developed for the synthesis of dimeric flavanol analogues under metal-free and mild conditions. Its applicability is showcased by the efficient synthesis of bisflav

Total synthesis of (-)-bis-8,8′-catechinylmethane isolated from cocoa liquor

An efficient synthesis of bis-8,8′-catechinylmethane, a dimeric flavanol linked through a methylene bridge, is described. Our strategy involved a regioselective coupling via a trifluoroacetic anhydride condensation reaction followed by ketone reduction to the methylene employing new conditions (lithium aluminum hydride and hexafluorophosphoric acid).

Hydrogenation of substituted aromatic aldehydes: Nucleophilic trapping of the reaction intermediate, application to the efficient synthesis of methylene linked flavanol dimers

The synthesis of dimeric flavanols is the consequence of the possible trapping of the reaction intermediates generated in the course of the reductive hydrogenation of substituted benzaldehydes. The scope of this reaction is investigated.