81558-23-8 Usage
Uses
Used in Pharmaceutical Synthesis:
2,3,3-Trimethyl-6-(trifluoromethyl)-3H-indole is used as a key building block for the development of new pharmaceuticals, leveraging its unique chemical structure to create novel drug candidates.
Used in Agrochemical Production:
2,3,3-Trimethyl-6-(trifluoromethyl)-3H-indole is employed as a reagent in the synthesis of agrochemicals, contributing to the development of innovative products for agricultural applications.
Used in Organic Material Synthesis:
2,3,3-Trimethyl-6-(trifluoromethyl)-3H-indole is utilized in the creation of organic materials, where its properties can be harnessed to produce advanced materials with specific characteristics.
Used in Organic Synthesis as a Reagent:
Due to its reactivity, 2,3,3-Trimethyl-6-(trifluoromethyl)-3H-indole is used as a reagent in various organic synthesis processes, facilitating the production of a wide range of chemical compounds.
Used in Analytical and Biological Applications:
The potent fluorescent properties of 2,3,3-Trimethyl-6-(trifluoromethyl)-3H-indole make it a valuable tool in analytical and biological research, where it can be used to track and study various biological processes.
Used in Medicinal Chemistry and Drug Development:
2,3,3-Trimethyl-6-(trifluoromethyl)-3H-indole is used as a subject of study in medicinal chemistry, with its potential antibacterial, antiviral, and anticancer properties being explored for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 81558-23-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,5,5 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81558-23:
(7*8)+(6*1)+(5*5)+(4*5)+(3*8)+(2*2)+(1*3)=138
138 % 10 = 8
So 81558-23-8 is a valid CAS Registry Number.
81558-23-8Relevant academic research and scientific papers
Preparation of Indolenines via Nucleophilic Aromatic Substitution
Huber, Florian,Roesslein, Joel,Gademann, Karl
supporting information, p. 2560 - 2564 (2019/03/19)
An unusual aromatic substitution to access indolenines is described. 2-(2-Methoxyphenyl)acetonitrile derivatives are reacted with various alkyl and aryl Li reagents to furnish the corresponding indolenine products, constituents of natural products, and cyanine dyes such as indocyanine green. This new method was used to synthesize 41 indolenines with large functional group tolerance, and selected examples were further converted to the corresponding indolenine dyes. Key experiments provide insight into the mechanism of this nucleophilic aromatic substitution.
CYANINE DYES FROM DERIVATIVES OF 4-, 5-, and 6-TRIFLUOROMETHYLINDOLENINES
Troitskaya, V. I.,Oksengendler, I. G.,Pazenok, S. V.,Lyubich, M. S.,Larina, S. M.,Yagupol'skii, L. M.
, p. 39 - 43 (2007/10/02)
The synthesis of 2,3-dimethyl-5- and -6-trifluoromethylindoles and 2,3,3-trimethyl-4-, -5-, and -6-trifluoromethylindolenines, from which quarternary salts, as well as indocarbo- and di- and tricarbocyanine dyes were obtained, is described.The effect of the introduction of a trifluoromethyl group in the 4, 5, and 6 positions on the color of the indocyanine dyes is examined.
