81558-23-8 Usage
General Description
2,3,3-Trimethyl-6-(trifluoromethyl)-3H-indole is a chemical compound with the molecular formula C14H13F3N. It is a bright yellow solid that is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and organic materials. 2,3,3-Trimethyl-6-(trifluoromethyl)-3H-indole is often used as a reagent in organic synthesis due to its unique properties and reactivity. It is also known for its potent fluorescent properties, which make it useful in various analytical and biological applications. The compound has shown potential in various studies for its antibacterial, antiviral, and anticancer properties, making it a subject of interest in the field of medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 81558-23-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,5,5 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81558-23:
(7*8)+(6*1)+(5*5)+(4*5)+(3*8)+(2*2)+(1*3)=138
138 % 10 = 8
So 81558-23-8 is a valid CAS Registry Number.
81558-23-8Relevant articles and documents
Preparation of Indolenines via Nucleophilic Aromatic Substitution
Huber, Florian,Roesslein, Joel,Gademann, Karl
supporting information, p. 2560 - 2564 (2019/03/19)
An unusual aromatic substitution to access indolenines is described. 2-(2-Methoxyphenyl)acetonitrile derivatives are reacted with various alkyl and aryl Li reagents to furnish the corresponding indolenine products, constituents of natural products, and cyanine dyes such as indocyanine green. This new method was used to synthesize 41 indolenines with large functional group tolerance, and selected examples were further converted to the corresponding indolenine dyes. Key experiments provide insight into the mechanism of this nucleophilic aromatic substitution.
