815581-77-2

Basic information

• Product Name: [(1S,5R)-5-hydroxy-2,6,6-trimethylcyclohex-2-enyl]methyl 4-bromobenzoate
• Synonyms: [(1S,5R)-5-hydroxy-2,6,6-trimethylcyclohex-2-enyl]methyl 4-bromobenzoate
• CAS NO: 815581-77-2
• Molecular Weight: 353.256
• Mol File: 815581-77-2.mol

Chemical Properties

• CAS DataBase Reference: [(1S,5R)-5-hydroxy-2,6,6-trimethylcyclohex-2-enyl]methyl 4-bromobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: [(1S,5R)-5-hydroxy-2,6,6-trimethylcyclohex-2-enyl]methyl 4-bromobenzoate(815581-77-2)
• EPA Substance Registry System: [(1S,5R)-5-hydroxy-2,6,6-trimethylcyclohex-2-enyl]methyl 4-bromobenzoate(815581-77-2)

Safety Data

• Hazardous Substances Data: 815581-77-2(Hazardous Substances Data)

Upstream product

• 586-75-4 4-chlorobenzoyl chloride 
• 815581-75-0 (1S,5R)-5-(hydroxymethyl)-4,6,6-trimethylcyclohex-3-enol 
• 86561-84-4 essigsaeure-<(E,R)-6,7-dihydroxy-3,7-dimethyl-2-octenyl>ester 
• 86561-83-3 (S,E)-5-(3,3-dimethyloxiran-2-yl)-3-methylpent-2-en-1-ol 

Downstream Products

• 815581-80-7 (RS)-1-[(S)-2,6,6-trimethylcyclohex-2-enyl]but-3-en-1-ol 
• 221046-97-5 (S,3E)-4-[(S)-2,6,6-trimethylcyclohex-2-enyl]but-3-en-2-ol 
• 174198-90-4 [(S)-2,6,6-trimethylcyclohex-2-enyl]but-3-en-1-one 
• 116497-11-1 (2E)-1-[(S)-2,6,6-trimethylcyclohex-2-enyl]but-2-en-1-one 
• 14398-36-8 (3E)-4-[(S)-2,6,6-trimethylcyclohex-2-enyl]but-3-en-2-one 
• 14505-74-9 (S)-2,6,6-trimethylcyclohex-2-enecarbaldehyde 
• 52646-93-2 [(S)-2,6,6-trimethylcyclohex-2-enyl]methanol 
• 69297-41-2 ((S)-2,6,6-Trimethyl-cyclohex-2-enylmethylsulfanyl)-benzene 
• 24190-29-2 (R)-α-ionone 
• 815581-83-0 (S)-1-Benzenesulfonyl-3-(tert-butyl-diphenyl-silanyloxy)-1-((S)-2,6,6-trimethyl-cyclohex-2-enyl)-butan-2-ol 
• 815581-84-1 tert-Butyl-[(E)-(S)-1-methyl-3-((S)-2,6,6-trimethyl-cyclohex-2-enyl)-allyloxy]-diphenyl-silane 
• 815581-78-3 [(R)-2,6,6-trimethylcyclohexa-2,4-dienyl]methyl 4-bromobenzoate 
• 815581-82-9 1-[((S)-2,6,6-trimethylcyclohex-2-enyl)methylsulfonyl]benzene 
• 1026627-42-8 4-Bromo-benzoic acid (1R,5S)-5-methanesulfonyloxy-2,6,6-trimethyl-cyclohex-2-enylmethyl ester 

Relevant articles and documents

A simple and efficient highly enantioselective synthesis of α-ionone and α-damascone

An efficient highly enantioselective (ee ≥99%) synthesis of α-ionone and α-damascone is described. Both enantiomers of title compounds were synthesized through two straightforward pathways diverging from enantiopure (R)- or (S)-α-cyclogeraniol. These versatile building blocks were obtained by regioselective ZrCl4-promoted biomimetic cyclization of (6S)- or (6E)-(Z)-6,7-epoxygeraniol, respectively, followed by deoxygenation of the so formed secondary alcohol. The chiral information was encoded by a highly regioselecive Sharpless asymmetric dihydroxylation of inexpensive geranyl acetate.