81559-95-7Relevant academic research and scientific papers
Mannich bases as synthetic intermediates: Synthesis of 3- and 4-functionalized 2-pyrazolines
Afsah, Elsayed M.,Kandeel, Ez-El-Din M.,Khalifa, Mona M.,Hammouda, Waleed M.
, p. 540 - 548 (2007/10/03)
The reaction of styryl ketonic Mannich bases 2a - c with phenylhydrazine leads to 3-functionalized 2-pyrazolines 4 or 6 depending on the reaction conditions. 3-[β-(Arylamino)ethyl]-2-pyrazolines 8a,b were obtained via transamination between the methiodide
Antiviral 1-aryl-5-amino-1-penten-3-ones
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, (2008/06/13)
Compounds of the formula STR1 wherein R is H, halo, C1-4 alkyl, C1-4 alkoxy, 3,4-methylenedioxy, CF3, NO2, NH2, N(C1-4 alkyl)2, CN, OH, --S(C1-4 alkyl) or --SO2/
Mannich Bases of 4-Phenyl-3-buten-2-one: A New Class of Antiherpes Agent
Edwards, M.L.,Ritter, H.W.,Stemerick, D.M.,Stewart, K.T.
, p. 431 - 436 (2007/10/02)
The morpholine Mannich base of 4-phenyl-3-buten-2-one was found to have activity in model infections of herpes simplex.The activity was essentially equivalent to that of disodium phosphonoacetate.This paper presents the biological activity and synthesis o
