81562-40-5Relevant academic research and scientific papers
Cyclization Reactions of β,γ-Unsaturated Derivatives of Carbonic Acid. VII. Synthesis of Unequivocal N-Acylated Thiazolidine-2-ones and Oxazolidine-2-ones
Widera, R.,Muehlstaedt, M.
, p. 1005 - 1010 (2007/10/02)
A new synthetic route to N-acylated thiazolidine-2-ones and oxazolidine-2-ones is reported: The reaction of carboxylic acid chlorides with 2-alkoxy-2-thiazolines (1,2) or -2-oxazolines (3) yields unequivocal N-acylated thiazolidine-2-ones (4-6) or oxazolidine-2-ones (7).Bifunctional acid chlorides, e.g. oxalyl chloride or thiophosgene yield compounds 11 and 12.
