81568-79-8Relevant academic research and scientific papers
Hydrosilane-Mediated Electrochemical Reduction of Amides
Okamoto, Kazuhiro,Nagahara, Shingo,Imada, Yasushi,Narita, Risako,Kitano, Yoshikazu,Chiba, Kazuhiro
, p. 15992 - 16000 (2021)
Electrochemical reduction of amides was achieved by using a hydrosilane without any toxic or expensive metals. The key reactive ketyl radical intermediate was generated by cathodic reduction. Continuous reaction with anodically generated silyl radicals or zinc bromide resulted in chemoselective deoxygenation to give the corresponding amines.
Electrochemical Reactions. Part 24. Reductive Cyclisation of i-(2-Halogenophenyl)-j-phenyl Compounds: A General Reaction
Grimshaw, James,Hamilton, Robert,Trocha-Grimshaw, Jadwiga
, p. 229 - 234 (2007/10/02)
The phenyl ?-radical formed by reduction of aryl halides in an aprotic solvent undergoes efficient radical substitution on an adjacent benzene ring.Several examples of this cyclisation reaction are given.The reaction is appropriate for the synthesis of 6-membered aromatic rings where the two reacting phenyl groups are held in a cis-configuration by an olefin bond or another aromatic ring.
