81583-87-1

Upstream product

• 81583-86-0 6-tert-Butyl-2-((S)-1-phenyl-ethyl)-1-oxa-2-aza-spiro[2.5]octane 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 81583-86-0 (2R,αS)-6(e)-tert-butyl-2-(α-methylbenzyl)-1,2-oxazaspiro<2.5>octane 
• 81583-85-9 (-)-(S)-N-(4-tert-butylcyclohexylidene)-α-methylbenzylamine 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 81583-85-9 (4-tert-Butyl-cyclohexylidene)-((S)-1-phenyl-ethyl)-amine 
• 116837-82-2 <2S^*(R^*),3(trans)>-6-(1,1-dimethylethyl)-2-(1'-phenylethyl)-1-oxa-2-azaspiro<2.5>octane 
• 81583-86-0 6-(1,1-dimethylethyl)-2-(1'-phenylethyl)-1-oxa-2-azaspiro<2.5>octane 

Relevant academic research and scientific papers

Photochemical Rearrangement of Chiral Oxaziridines in Continuous Flow: Application Toward the Scale-Up of a Chiral Bicyclic Lactam

A method for synthesizing chiral lactams from chiral oxaziridines in continuous flow is described. The oxaziridines are readily available from cyclic ketones. Photolysis of the oxaziridines using the Booker-Milburn flow system provides conversion to the chiral lactams in good yield and short residence times. Application of this chemistry toward the synthesis of a chiral bicyclic lactam is described.

SELECTIVITY IN AN ASYMMETRIC NITROGEN INSERTION PROCESS

A simple and efficient synthesis of chiral lactams utilizing a group-selective nitrogen insertion process has been investigated for a group of prochiral ketones.The preparation of a useful intermediate in benzomorphinan synthesis has been carried out in o

Photochemical and Thermal Rearrangement of Oxaziridines. Experimental Evidence in Support of the Stereoelectronic Control Theory

The irradiation of an optically pure isomer of a spirooxaziridine, (2R,αS)-6(e)-tert-butyl-2-(α-methylbenzyl)-1,2-oxazaspirooctane, gave a single lactam, (5S,αS)-5-tert-butyl-1-(α-methylbenzyl)hexahydro-2-azepinone.The absolute configurations of thes