81643-01-8Relevant academic research and scientific papers
Rh2(R -TPCP)4-catalyzed enantioselective [3+2]-cycloaddition between nitrones and vinyldiazoacetates
Qin, Changming,Davies, Huw M. L.
supporting information, p. 14516 - 14519 (2013/10/22)
Rhodium-catalyzed reaction of vinyldiazoacetates with nitrones results in a formal [3+2]-cycloaddition to generate 2,5-dihydroisoxazoles with high levels of asymmetric induction. The cascade reaction begins with a vinylogous addition event, followed by an iminium addition ring-closure/hydride migration/alkene isomerization cascade. Dirhodium tetrakis(triarylcyclopropanecarboxylates) are the optimum catalysts for this process.
Stereochemical consequences in the deprotonation of enoates
Galatsis, Paul,Manwell, Jeffrey J.,Millan, Scott D.
, p. 5261 - 5264 (2007/10/03)
A cyclic transition structure for the deprotonation of enoates was proposed to rationalize the geometry of the deconjugated olefin and the substrate reactivity patterns.
Double Bond Stabilizing Abilities of Formyl, Carbo-tert-butoxy, and Carbomethoxy Substituents
Hine, Jack,Kanagasabapathy, V.M.,Ng, Peter
, p. 2745 - 2748 (2007/10/02)
Equilibrium constants for reactions of the type trans-MeCH=CHCH2COX trans-EtCH=CHCOX, where X is H, OMe, and O-t-Bu, have been determined in tert-butyl alcohol solution at various temperatures by using basic catalysts.These equilibrium constants for formation of the conjugated isomer, extrapolated to 25 deg C, are 24, 4.9, and 5.1 for the aldehyde, methyl ester, and tert-butyl ester, respectively.Possible explanations for the relative magnitudes of these equilibrium constants are discussed.
