816447-26-4

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 2108-53-4 3-(4-Methoxyphenyl)-2-cyclopenten-1-one 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 930-30-3 cyclopent-2-enone 
• 816447-25-3 3-(4-methoxyphenyl)-4-phenylcyclopent-2-en-1-one 

Downstream Products

• 816447-27-5 2-[2-(benzyloxy)phenyl]-3-(4-methoxyphenyl)-4-phenylcyclopent-2-en-1-one 

Relevant academic research and scientific papers

Synthesis of 2,3,4-Trisubstituted 2-Cyclopentenones via Sequential Functionalization of 2-Cyclopentenone

The synthesis of differently substituted 2,3,4-triarylcyclopent-2-en-1-ones from 2-cyclopentenone via sequential functionalization of a novel 2,4-dibromo-3-(4-methoxyphenyl) cyclopent-2-en-1-one intermediate has been developed. The process provides access

Stereoselective synthesis of (±)-rocaglaol analogues

(Chemical equation presented) An intramolecular hydroxy epoxide opening was used to access the cyclopenta[d]benzofuran ring system of the natural product rocaglaol (2). Our route allowed the stereocontrolled preparation of the rocaglaol derivative (±)-(1S*,3S*,3aR*,8bS*)-3b. The synthesis of the (±)-(3R*)-epimer of 3b was also achieved. Our strategy is well-suited for the production of analogues with variation of the western ring.