816451-57-7Relevant academic research and scientific papers
Process for chemically removing the acyl sidechain from cephalosporins and penicillins
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, (2008/06/13)
A process for removing the acyl sidechain from penicillins and cephalosporins which comprises chlorinating the acyl compound and treating the resulting iminochloride with an o-aminothiophenol to obtain the corresponding 6β-aminopenicillin or 7β-aminocephalosporin.
Arylmalonamidomethoxycephalosporins
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, (2008/06/13)
Antibacterial 7β-arylmalonamido-7α-methoxy-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids of the formula: STR1 wherein Ar is a heterocyclic group or p-oxysubstituted phenyl; COB1 and COB2 are each a carboxy or protected carbox
7-Methoxycephalosporins
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, (2008/06/13)
7β-acylamido-7α-methoxycephalosporin compounds in which the acylamido group has the formula SPC1 In which R is carboxy, protected carboxy, phosphono, protected phosphono, sulfo, or protected sulfo. The compounds exhibit antibiotic activity, in particular
