816453-91-5Relevant academic research and scientific papers
Heterocyclized carbometalation of alkynes: Unexpected formation of eight-membered oxazirconacycles with an intramolecularly coordinated isoquinoline moiety
Zhou, Shaolin,Liu, Dongyun,Liu, Yuanhong
, p. 5900 - 5902 (2004)
The isoquinolyl-zirconation of various unactivated alkynes was investigated by a one-pot, three-component reaction of two different alkynes with a nitrile in the presence of 1 equiv of CuCl. The true nature of the resulting products of novel eight-membered oxazirconacycles containing an intramolecular Zr-N coordination was established using X-ray crystallography.
